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    Results: 1 to 20 of 289

    1.

    Peroxisome proliferator-activated receptor (PPAR)-alpha activation lowers muscle lipids and improves insulin sensitivity in high fat-fed rats: comparison with PPAR-gamma activation.

    Ye JM, Doyle PJ, Iglesias MA, Watson DG, Cooney GJ, Kraegen EW.

    Diabetes. 2001 Feb;50(2):411-7.PMID: 11272155 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    PPARalpha /gamma ragaglitazar eliminates fatty liver and enhances insulin action in fat-fed rats in the absence of hepatomegaly.

    Ye JM, Iglesias MA, Watson DG, Ellis B, Wood L, Jensen PB, Sørensen RV, Larsen PJ, Cooney GJ, Wassermann K, Kraegen EW.

    Am J Physiol Endocrinol Metab. 2003 Mar;284(3):E531-40.PMID: 12556350 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Peroxisome proliferator-activated receptor (PPAR) activation induces tissue-specific effects on fatty acid uptake and metabolism in vivo--a study using the novel PPARalpha/gamma agonist tesaglitazar.

    Hegarty BD, Furler SM, Oakes ND, Kraegen EW, Cooney GJ.

    Endocrinology. 2004 Jul;145(7):3158-64. Epub 2004 Apr 1.PMID: 15059948 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Peroxisome proliferator-activated receptor-alpha deficiency does not alter insulin sensitivity in mice maintained on regular or high-fat diet: hyperinsulinemic-euglycemic clamp studies.

    Haluzik M, Gavrilova O, LeRoith D.

    Endocrinology. 2004 Apr;145(4):1662-7. Epub 2003 Dec 11.PMID: 14670996 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Diet-induced muscle insulin resistance in rats is ameliorated by acute dietary lipid withdrawal or a single bout of exercise: parallel relationship between insulin stimulation of glucose uptake and suppression of long-chain fatty acyl-CoA.

    Oakes ND, Bell KS, Furler SM, Camilleri S, Saha AK, Ruderman NB, Chisholm DJ, Kraegen EW.

    Diabetes. 1997 Dec;46(12):2022-8.PMID: 9392490 [PubMed - indexed for MEDLINE]Related articles

    6.

    Differential influences of peroxisome proliferator-activated receptors gamma and -alpha on food intake and energy homeostasis.

    Larsen PJ, Jensen PB, Sørensen RV, Larsen LK, Vrang N, Wulff EM, Wassermann K.

    Diabetes. 2003 Sep;52(9):2249-59.PMID: 12941763 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Pioglitazone can ameliorate insulin resistance in low-dose streptozotocin and high sucrose-fat diet induced obese rats.

    Ding SY, Shen ZF, Chen YT, Sun SJ, Liu Q, Xie MZ.

    Acta Pharmacol Sin. 2005 May;26(5):575-80.PMID: 15842776 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats.

    Lee HJ, Choi SS, Park MK, An YJ, Seo SY, Kim MC, Hong SH, Hwang TH, Kang DY, Garber AJ, Kim DK.

    Biochem Biophys Res Commun. 2002 Aug 16;296(2):293-9.PMID: 12163016 [PubMed - indexed for MEDLINE]Related articles

    9.

    Effects of peroxisome proliferator-activated receptor (PPAR)-alpha and PPAR-gamma agonists on glucose and lipid metabolism in patients with type 2 diabetes mellitus.

    Bajaj M, Suraamornkul S, Hardies LJ, Glass L, Musi N, DeFronzo RA.

    Diabetologia. 2007 Aug;50(8):1723-31. Epub 2007 May 23.PMID: 17520238 [PubMed - indexed for MEDLINE]Related articles

    10.

    Peroxisome proliferator-activated receptor (PPAR)-alpha agonism prevents the onset of type 2 diabetes in Zucker diabetic fatty rats: A comparison with PPAR gamma agonism.

    Bergeron R, Yao J, Woods JW, Zycband EI, Liu C, Li Z, Adams A, Berger JP, Zhang BB, Moller DE, Doebber TW.

    Endocrinology. 2006 Sep;147(9):4252-62. Epub 2006 May 25.PMID: 16728496 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Triglycerides, fatty acids and insulin resistance--hyperinsulinemia.

    Kraegen EW, Cooney GJ, Ye J, Thompson AL.

    Exp Clin Endocrinol Diabetes. 2001;109(4):S516-26. Review.PMID: 11453039 [PubMed - indexed for MEDLINE]Related articles

    12.

    Isohumulones, bitter acids derived from hops, activate both peroxisome proliferator-activated receptor alpha and gamma and reduce insulin resistance.

    Yajima H, Ikeshima E, Shiraki M, Kanaya T, Fujiwara D, Odai H, Tsuboyama-Kasaoka N, Ezaki O, Oikawa S, Kondo K.

    J Biol Chem. 2004 Aug 6;279(32):33456-62. Epub 2004 Jun 3.PMID: 15178687 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    A novel insulin sensitizer acts as a coligand for peroxisome proliferator-activated receptor-alpha (PPAR-alpha) and PPAR-gamma: effect of PPAR-alpha activation on abnormal lipid metabolism in liver of Zucker fatty rats.

    Murakami K, Tobe K, Ide T, Mochizuki T, Ohashi M, Akanuma Y, Yazaki Y, Kadowaki T.

    Diabetes. 1998 Dec;47(12):1841-7.PMID: 9836514 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Peroxisome proliferator-activated receptor (PPAR)-alpha activation prevents diabetes in OLETF rats: comparison with PPAR-gamma activation.

    Koh EH, Kim MS, Park JY, Kim HS, Youn JY, Park HS, Youn JH, Lee KU.

    Diabetes. 2003 Sep;52(9):2331-7.PMID: 12941773 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Mechanisms of liver and muscle insulin resistance induced by chronic high-fat feeding.

    Oakes ND, Cooney GJ, Camilleri S, Chisholm DJ, Kraegen EW.

    Diabetes. 1997 Nov;46(11):1768-74.PMID: 9356024 [PubMed - indexed for MEDLINE]Related articles

    16.

    PPAR-alpha-null mice are protected from high-fat diet-induced insulin resistance.

    Guerre-Millo M, Rouault C, Poulain P, André J, Poitout V, Peters JM, Gonzalez FJ, Fruchart JC, Reach G, Staels B.

    Diabetes. 2001 Dec;50(12):2809-14.PMID: 11723064 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Comprehensive messenger ribonucleic acid profiling reveals that peroxisome proliferator-activated receptor gamma activation has coordinate effects on gene expression in multiple insulin-sensitive tissues.

    Way JM, Harrington WW, Brown KK, Gottschalk WK, Sundseth SS, Mansfield TA, Ramachandran RK, Willson TM, Kliewer SA.

    Endocrinology. 2001 Mar;142(3):1269-77.PMID: 11181544 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Improvement of insulin sensitivity after peroxisome proliferator-activated receptor-alpha agonist treatment is accompanied by paradoxical increase of circulating resistin levels.

    Haluzik MM, Lacinova Z, Dolinkova M, Haluzikova D, Housa D, Horinek A, Vernerova Z, Kumstyrova T, Haluzik M.

    Endocrinology. 2006 Sep;147(9):4517-24. Epub 2006 Jun 1.PMID: 16740970 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    AICAR administration causes an apparent enhancement of muscle and liver insulin action in insulin-resistant high-fat-fed rats.

    Iglesias MA, Ye JM, Frangioudakis G, Saha AK, Tomas E, Ruderman NB, Cooney GJ, Kraegen EW.

    Diabetes. 2002 Oct;51(10):2886-94. Erratum in: Diabetes 2003 Jan;52(1):223-4. PMID: 12351423 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Interactive influences of peroxisome proliferator-activated receptor alpha activation and glucocorticoids on pancreatic beta cell compensation in insulin resistance induced by dietary saturated fat in the rat.

    Holness MJ, Smith ND, Greenwood GK, Sugden MC.

    Diabetologia. 2005 Oct;48(10):2062-8. Epub 2005 Aug 19.PMID: 16132960 [PubMed - indexed for MEDLINE]Related articles

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