PubMed

Hypoglycemic detection does not occur in the hepatic artery or liver: findings consistent with a portal vein glucosensor locus.

Hevener AL, Bergman RN, Donovan CM.

Diabetes. 2001 Feb;50(2):399-403.PMID: 11272153 [PubMed - indexed for MEDLINE]Related articlesFree article

Novel glucosensor for hypoglycemic detection localized to the portal vein.

Hevener AL, Bergman RN, Donovan CM.

Diabetes. 1997 Sep;46(9):1521-5.PMID: 9287058 [PubMed - indexed for MEDLINE]Related articles

Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia.

Hevener AL, Bergman RN, Donovan CM.

Diabetes. 2000 Jan;49(1):8-12.PMID: 10615943 [PubMed - indexed for MEDLINE]Related articlesFree article

Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia.

Donovan CM, Halter JB, Bergman RN.

Diabetes. 1991 Jan;40(1):155-8.PMID: 1849847 [PubMed - indexed for MEDLINE]Related articles

The role of liver glucosensors in the integrated sympathetic response induced by deep hypoglycemia in dogs.

Hamilton-Wessler M, Bergman RN, Halter JB, Watanabe RM, Donovan CM.

Diabetes. 1994 Aug;43(8):1052-60.PMID: 8039600 [PubMed - indexed for MEDLINE]Related articles

Celiac-superior mesenteric ganglionectomy, but not vagotomy, suppresses the sympathoadrenal response to insulin-induced hypoglycemia.

Fujita S, Donovan CM.

Diabetes. 2005 Nov;54(11):3258-64.PMID: 16249453 [PubMed - indexed for MEDLINE]Related articlesFree article

Primacy of liver glucosensors in the sympathetic response to progressive hypoglycemia.

Donovan CM, Hamilton-Wessler M, Halter JB, Bergman RN.

Proc Natl Acad Sci U S A. 1994 Mar 29;91(7):2863-7.PMID: 8146201 [PubMed - indexed for MEDLINE]Related articlesFree article

The locus for hypoglycemic detection shifts with the rate of fall in glycemia: the role of portal-superior mesenteric vein glucose sensing.

Saberi M, Bohland M, Donovan CM.

Diabetes. 2008 May;57(5):1380-6. Epub 2008 Feb 21.PMID: 18292347 [PubMed - indexed for MEDLINE]Related articlesFree article

In the absence of counterregulatory hormones, the increase in hepatic glucose production during insulin-induced hypoglycemia in the dog is initiated in the liver rather than the brain.

Connolly CC, Myers SR, Neal DW, Hastings JR, Cherrington AD.

Diabetes. 1996 Dec;45(12):1805-13.PMID: 8922369 [PubMed - indexed for MEDLINE]Related articles

Portal venous 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside infusion overcomes hyperinsulinemic suppression of endogenous glucose output.

Camacho RC, Pencek RR, Lacy DB, James FD, Donahue EP, Wasserman DH.

Diabetes. 2005 Feb;54(2):373-82.PMID: 15677495 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of hyperinsulinemia on the subsequent hormonal response to hypoglycemia in conscious dogs.

Davis SN, Dobbins R, Colburn C, Tarumi C, Jacobs J, Neal D, Cherrington AD.

Am J Physiol. 1993 May;264(5 Pt 1):E748-55.PMID: 8498496 [PubMed - indexed for MEDLINE]Related articles

Basal hepatic glucose production is regulated by the portal vein insulin concentration.

Sindelar DK, Chu CA, Venson P, Donahue EP, Neal DW, Cherrington AD.

Diabetes. 1998 Apr;47(4):523-9.PMID: 9568682 [PubMed - indexed for MEDLINE]Related articlesFree article

Metabolic sensors mediate hypoglycemic detection at the portal vein.

Matveyenko AV, Donovan CM.

Diabetes. 2006 May;55(5):1276-82.PMID: 16644683 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of a selective rise in hepatic artery insulin on hepatic glucose production in the conscious dog.

Sindelar DK, Igawa K, Chu CA, Balcom JH, Neal DW, Cherrington AD.

Am J Physiol. 1999 Apr;276(4 Pt 1):E806-13.PMID: 10198319 [PubMed - indexed for MEDLINE]Related articlesFree article

Both positive and negative portal venous and hepatic arterial glucose gradients stimulate hepatic glucose uptake after the same amount of glucose is infused into the splanchnic bed in conscious dogs.

Horikawa S, Ishida T, Igawa K, Kawanishi K, Hartley CJ, Takahara J.

Metabolism. 1998 Nov;47(11):1295-302.PMID: 9826203 [PubMed - indexed for MEDLINE]Related articles

Importance of the hepatic arterial glucose level in generation of the portal signal in conscious dogs.

Hsieh PS, Moore MC, Neal DW, Cherrington AD.

Am J Physiol Endocrinol Metab. 2000 Aug;279(2):E284-92.PMID: 10913027 [PubMed - indexed for MEDLINE]Related articlesFree article

Putative hypothalamic glucoreceptors play no essential role in the response to moderate hypoglycemia.

Cane P, Artal R, Bergman RN.

Diabetes. 1986 Mar;35(3):268-77.PMID: 3005093 [PubMed - indexed for MEDLINE]Related articles

Counterregulatory response to hypoglycemia differs according to the insulin delivery route, but does not affect glucose production in normal humans.

Lewis GF, Carpentier A, Bilinski D, Giacca A, Vranic M.

J Clin Endocrinol Metab. 1999 Mar;84(3):1037-46.PMID: 10084592 [PubMed - indexed for MEDLINE]Related articlesFree article

5-Aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside renders glucose output by the liver of the dog insensitive to a pharmacological increment in insulin.

Camacho RC, Lacy DB, James FD, Donahue EP, Wasserman DH.

Am J Physiol Endocrinol Metab. 2005 Dec;289(6):E1039-43. Epub 2005 Jul 26.PMID: 16046457 [PubMed - indexed for MEDLINE]Related articlesFree article

Hypoglycemic detection at the portal vein is mediated by capsaicin-sensitive primary sensory neurons.

Fujita S, Bohland M, Sanchez-Watts G, Watts AG, Donovan CM.

Am J Physiol Endocrinol Metab. 2007 Jul;293(1):E96-E101. Epub 2007 Mar 20.PMID: 17374696 [PubMed - indexed for MEDLINE]Related articlesFree article