PubMed

Characterization of a KATP channel-independent pathway involved in potentiation of insulin secretion by efaroxan.

Chan SL, Mourtada M, Morgan NG.

Diabetes. 2001 Feb;50(2):340-7.PMID: 11272145 [PubMed - indexed for MEDLINE]Related articlesFree article

Essential role of the imidazoline moiety in the insulinotropic effect but not the KATP channel-blocking effect of imidazolines; a comparison of the effects of efaroxan and its imidazole analogue, KU14R.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetologia. 2005 Dec;48(12):2567-75. Epub 2005 Nov 11.PMID: 16283242 [PubMed - indexed for MEDLINE]Related articles

Clotrimazole and efaroxan stimulate insulin secretion by different mechanisms in rat pancreatic islets.

Chan SL, Pallett AL, Morgan NG.

Naunyn Schmiedebergs Arch Pharmacol. 1997 Dec;356(6):763-8.PMID: 9453462 [PubMed - indexed for MEDLINE]Related articles

ATP-sensitive potassium channels and efaroxan-induced insulin release in the electrofusion-derived BRIN-BD11 beta-cell line.

Chapman JC, McClenaghan NH, Cosgrove KE, Hashmi MN, Shepherd RM, Giesberts AN, White SJ, Ammälä C, Flatt PR, Dunne MJ.

Diabetes. 1999 Dec;48(12):2349-57.PMID: 10580423 [PubMed - indexed for MEDLINE]Related articlesFree article

cAMP enhances insulin secretion by an action on the ATP-sensitive K+ channel-independent pathway of glucose signaling in rat pancreatic islets.

Yajima H, Komatsu M, Schermerhorn T, Aizawa T, Kaneko T, Nagai M, Sharp GW, Hashizume K.

Diabetes. 1999 May;48(5):1006-12.PMID: 10331404 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose dependence of imidazoline-induced insulin secretion: different characteristics of two ATP-Sensitive K+ channel-blocking compounds.

Bleck C, Wienbergen A, Rustenbeck I.

Diabetes. 2004 Dec;53 Suppl 3:S135-9.PMID: 15561901 [PubMed - indexed for MEDLINE]Related articlesFree article

Effector systems involved in the insulin secretory responses to efaroxan and RX871024 in rat islets of Langerhans.

Mourtada M, Smith SA, Morgan NG.

Eur J Pharmacol. 1998 Jun 5;350(2-3):251-8.PMID: 9696415 [PubMed - indexed for MEDLINE]Related articles

Antagonism of the stimulatory effects of efaroxan and glibenclamide in rat pancreatic islets by the imidazoline, RX801080.

Brown CA, Chan SL, Stillings MR, Smith SA, Morgan NG.

Br J Pharmacol. 1993 Nov;110(3):1017-22.PMID: 7905338 [PubMed - indexed for MEDLINE]Related articlesFree article

The alpha 2-adrenoceptor antagonist efaroxan modulates K+ATP channels in insulin-secreting cells.

Chan SL, Dunne MJ, Stillings MR, Morgan NG.

Eur J Pharmacol. 1991 Oct 29;204(1):41-8.PMID: 1687123 [PubMed - indexed for MEDLINE]Related articles

Stimulation of insulin secretion by efaroxan may involve interaction with potassium channels.

Chan SL, Morgan NG.

Eur J Pharmacol. 1990 Jan 25;176(1):97-101.PMID: 2178947 [PubMed - indexed for MEDLINE]Related articles

Interactions between imidazoline compounds and sulphonylureas in the regulation of insulin secretion.

Mourtada M, Brown CA, Smith SA, Piercy V, Chan SL, Morgan NG.

Br J Pharmacol. 1997 Jun;121(4):799-805.PMID: 9208151 [PubMed - indexed for MEDLINE]Related articlesFree article

Multiple effector pathways regulate the insulin secretory response to the imidazoline RX871024 in isolated rat pancreatic islets.

Mourtada M, Chan SL, Smith SA, Morgan NG.

Br J Pharmacol. 1999 Jul;127(5):1279-87.PMID: 10455276 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose triggers protein kinase A-dependent insulin secretion in mouse pancreatic islets through activation of the K+ATP channel-dependent pathway.

Thams P, Anwar MR, Capito K.

Eur J Endocrinol. 2005 Apr;152(4):671-7.PMID: 15817925 [PubMed - indexed for MEDLINE]Related articlesFree article

KATP channel-dependent and -independent pathways of insulin secretion in isolated islets from fa/fa Zucker rats.

Chan CB, MacPhail RM.

Biochem Cell Biol. 1996;74(3):403-10.PMID: 8883846 [PubMed - indexed for MEDLINE]Related articles

Evidence that the ability of imidazoline compounds to stimulate insulin secretion is not due to interaction with sigma receptors.

Chan SL, Pallett AL, Clews J, Ramsden CA, Morgan NG.

Eur J Pharmacol. 1997 Apr 4;323(2-3):241-4.PMID: 9128845 [PubMed - indexed for MEDLINE]Related articles

Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.

Sato Y, Anello M, Henquin JC.

Endocrinology. 1999 May;140(5):2252-7.PMID: 10218978 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of rise in cAMP levels on Ca2+ influx through voltage-dependent Ca2+ channels in HIT cells. Second-messenger synarchy in beta-cells.

Rajan AS, Hill RS, Boyd AE 3rd.

Diabetes. 1989 Jul;38(7):874-80.PMID: 2472299 [PubMed - indexed for MEDLINE]Related articles

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ.

J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8.PMID: 12414839 [PubMed - indexed for MEDLINE]Related articlesFree article

Triggering of insulin release by a combination of cAMP signal and nutrients: an ATP-sensitive K+ channel-independent phenomenon.

Komatsu M, Sato Y, Yamada S, Yamauchi K, Hashizume K, Aizawa T.

Diabetes. 2002 Feb;51 Suppl 1:S29-32.PMID: 11815454 [PubMed - indexed for MEDLINE]Related articlesFree article

Imidazoline NNC77-0074 stimulates insulin secretion and inhibits glucagon release by control of Ca(2+)-dependent exocytosis in pancreatic alpha- and beta-cells.

Høy M, Olsen HL, Andersen HS, Bokvist K, Buschard K, Hansen J, Jacobsen P, Petersen JS, Rorsman P, Gromada J.

Eur J Pharmacol. 2003 Apr 11;466(1-2):213-21.PMID: 12679159 [PubMed - indexed for MEDLINE]Related articles