PubMed

Hyperinsulinism of infancy: the regulated release of insulin by KATP channel-independent pathways.

Straub SG, Cosgrove KE, Ammälä C, Shepherd RM, O'Brien RE, Barnes PD, Kuchinski N, Chapman JC, Schaeppi M, Glaser B, Lindley KJ, Sharp GW, Aynsley-Green A, Dunne MJ.

Diabetes. 2001 Feb;50(2):329-39.PMID: 11272144 [PubMed - indexed for MEDLINE]Related articlesFree article

The structure and function of the ATP-sensitive K+ channel in insulin-secreting pancreatic beta-cells.

Miki T, Nagashima K, Seino S.

J Mol Endocrinol. 1999 Apr;22(2):113-23. Review.PMID: 10194514 [PubMed - indexed for MEDLINE]Related articlesFree article

Genotype-phenotype correlations in children with congenital hyperinsulinism due to recessive mutations of the adenosine triphosphate-sensitive potassium channel genes.

Henwood MJ, Kelly A, Macmullen C, Bhatia P, Ganguly A, Thornton PS, Stanley CA.

J Clin Endocrinol Metab. 2005 Feb;90(2):789-94. Epub 2004 Nov 23.PMID: 15562009 [PubMed - indexed for MEDLINE]Related articlesFree article

Sulfonylurea receptor 1 and Kir6.2 expression in the novel human insulin-secreting cell line NES2Y.

Macfarlane WM, O'Brien RE, Barnes PD, Shepherd RM, Cosgrove KE, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ.

Diabetes. 2000 Jun;49(6):953-60.PMID: 10866047 [PubMed - indexed for MEDLINE]Related articlesFree article

Both triggering and amplifying pathways contribute to fuel-induced insulin secretion in the absence of sulfonylurea receptor-1 in pancreatic beta-cells.

Nenquin M, Szollosi A, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2004 Jul 30;279(31):32316-24. Epub 2004 Jun 1.PMID: 15175349 [PubMed - indexed for MEDLINE]Related articlesFree article

Familial hyperinsulinism and pancreatic beta-cell ATP-sensitive potassium channels.

Sharma N, Crane A, Gonzalez G, Bryan J, Aguilar-Bryan L.

Kidney Int. 2000 Mar;57(3):803-8. Review.PMID: 10720932 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose stimulates Ca2+ influx and insulin secretion in 2-week-old beta-cells lacking ATP-sensitive K+ channels.

Szollosi A, Nenquin M, Aguilar-Bryan L, Bryan J, Henquin JC.

J Biol Chem. 2007 Jan 19;282(3):1747-56. Epub 2006 Nov 30.PMID: 17138557 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of insulin oversecretion by subcutaneous recombinant human insulin-like growth factor I in children with congenital hyperinsulinism due to defective beta-cell sulfonylurea receptor.

Katz LE, Ferry RJ Jr, Stanley CA, Collett-Solberg PF, Baker L, Cohen P.

J Clin Endocrinol Metab. 1999 Sep;84(9):3117-24.PMID: 10487673 [PubMed - indexed for MEDLINE]Related articlesFree article

H3 domain of syntaxin 1A inhibits KATP channels by its actions on the sulfonylurea receptor 1 nucleotide-binding folds-1 and -2.

Cui N, Kang Y, He Y, Leung YM, Xie H, Pasyk EA, Gao X, Sheu L, Hansen JB, Wahl P, Tsushima RG, Gaisano HY.

J Biol Chem. 2004 Dec 17;279(51):53259-65. Epub 2004 Oct 13.PMID: 15485808 [PubMed - indexed for MEDLINE]Related articlesFree article

Engineering a glucose-responsive human insulin-secreting cell line from islets of Langerhans isolated from a patient with persistent hyperinsulinemic hypoglycemia of infancy.

MacFarlane WM, Chapman JC, Shepherd RM, Hashmi MN, Kamimura N, Cosgrove KE, O'Brien RE, Barnes PD, Hart AW, Docherty HM, Lindley KJ, Aynsley-Green A, James RF, Docherty K, Dunne MJ.

J Biol Chem. 1999 Nov 26;274(48):34059-66.PMID: 10567373 [PubMed - indexed for MEDLINE]Related articlesFree article

Molecular biology of adenosine triphosphate-sensitive potassium channels.

Aguilar-Bryan L, Bryan J.

Endocr Rev. 1999 Apr;20(2):101-35. Review.PMID: 10204114 [PubMed - indexed for MEDLINE]Related articlesFree article

Carriers of an inactivating beta-cell ATP-sensitive K(+) channel mutation have normal glucose tolerance and insulin sensitivity and appropriate insulin secretion.

Huopio H, Vauhkonen I, Komulainen J, Niskanen L, Otonkoski T, Laakso M.

Diabetes Care. 2002 Jan;25(1):101-6.PMID: 11772909 [PubMed - indexed for MEDLINE]Related articlesFree article

Adenosine diphosphate as an intracellular regulator of insulin secretion.

Nichols CG, Shyng SL, Nestorowicz A, Glaser B, Clement JP 4th, Gonzalez G, Aguilar-Bryan L, Permutt MA, Bryan J.

Science. 1996 Jun 21;272(5269):1785-7.PMID: 8650576 [PubMed - indexed for MEDLINE]Related articles

Y-26763: ATP-sensitive K+ channel activation and the inhibition of insulin release from human pancreatic beta-cells.

Cosgrove KE, Straub SG, Barnes PD, Chapman J, Sharp GW, Dunne MJ.

Eur J Pharmacol. 2004 Feb 20;486(2):133-9.PMID: 14975702 [PubMed - indexed for MEDLINE]Related articles

Dysregulation of insulin secretion in children with congenital hyperinsulinism due to sulfonylurea receptor mutations.

Grimberg A, Ferry RJ Jr, Kelly A, Koo-McCoy S, Polonsky K, Glaser B, Permutt MA, Aguilar-Bryan L, Stafford D, Thornton PS, Baker L, Stanley CA.

Diabetes. 2001 Feb;50(2):322-8.PMID: 11272143 [PubMed - indexed for MEDLINE]Related articlesFree article

Crosstalk between membrane potential and cytosolic Ca2+ concentration in beta cells from Sur1-/- mice.

Haspel D, Krippeit-Drews P, Aguilar-Bryan L, Bryan J, Drews G, Düfer M.

Diabetologia. 2005 May;48(5):913-21. Epub 2005 Apr 14.PMID: 15830184 [PubMed - indexed for MEDLINE]Related articles

Loss of functional KATP channels in pancreatic beta-cells causes persistent hyperinsulinemic hypoglycemia of infancy.

Kane C, Shepherd RM, Squires PE, Johnson PR, James RF, Milla PJ, Aynsley-Green A, Lindley KJ, Dunne MJ.

Nat Med. 1996 Dec;2(12):1344-7.PMID: 8946833 [PubMed - indexed for MEDLINE]Related articles

Restitution of defective glucose-stimulated insulin release of sulfonylurea type 1 receptor knockout mice by acetylcholine.

Doliba NM, Qin W, Vatamaniuk MZ, Li C, Zelent D, Najafi H, Buettger CW, Collins HW, Carr RD, Magnuson MA, Matschinsky FM.

Am J Physiol Endocrinol Metab. 2004 May;286(5):E834-43. Epub 2004 Jan 21.PMID: 14736703 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.

Sato Y, Anello M, Henquin JC.

Endocrinology. 1999 May;140(5):2252-7.PMID: 10218978 [PubMed - indexed for MEDLINE]Related articlesFree article

BPDZ 154 activates adenosine 5'-triphosphate-sensitive potassium channels: in vitro studies using rodent insulin-secreting cells and islets isolated from patients with hyperinsulinism.

Cosgrove KE, Antoine MH, Lee AT, Barnes PD, de Tullio P, Clayton P, McCloy R, De Lonlay P, Nihoul-Fékété C, Robert JJ, Saudubray JM, Rahier J, Lindley KJ, Hussain K, Aynsley-Green A, Pirotte B, Lebrun P, Dunne MJ.

J Clin Endocrinol Metab. 2002 Nov;87(11):4860-8.PMID: 12414839 [PubMed - indexed for MEDLINE]Related articlesFree article