PubMed

Glucokinase gene locus transgenic mice are resistant to the development of obesity-induced type 2 diabetes.

Shiota M, Postic C, Fujimoto Y, Jetton TL, Dixon K, Pan D, Grimsby J, Grippo JF, Magnuson MA, Cherrington AD.

Diabetes. 2001 Mar;50(3):622-9.PMID: 11246883 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of high-fat diet on glucose homeostasis and gene expression in glucokinase knockout mice.

Gorman T, Hope DC, Brownlie R, Yu A, Gill D, Löfvenmark J, Wedin M, Mayers RM, Snaith MR, Smith DM.

Diabetes Obes Metab. 2008 Sep;10(10):885-97. Epub 2007 Nov 22.PMID: 18034843 [PubMed - indexed for MEDLINE]Related articles

GLUT-1 or GLUT-4 transgenes in obese mice improve glucose tolerance but do not prevent insulin resistance.

Marshall BA, Hansen PA, Ensor NJ, Ogden MA, Mueckler M.

Am J Physiol. 1999 Feb;276(2 Pt 1):E390-400.PMID: 9950801 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence from transgenic mice that glucokinase is rate limiting for glucose utilization in the liver.

Ferre T, Riu E, Bosch F, Valera A.

FASEB J. 1996 Aug;10(10):1213-8.PMID: 8751724 [PubMed - indexed for MEDLINE]Related articlesFree article

Long-term overexpression of glucokinase in the liver of transgenic mice leads to insulin resistance.

Ferre T, Riu E, Franckhauser S, Agudo J, Bosch F.

Diabetologia. 2003 Dec;46(12):1662-8. Epub 2003 Nov 12.PMID: 14614559 [PubMed - indexed for MEDLINE]Related articles

Prevention of obesity and insulin resistance by glucokinase expression in skeletal muscle of transgenic mice.

Otaegui PJ, Ferre T, Riu E, Bosch F.

FASEB J. 2003 Nov;17(14):2097-9. Epub 2003 Sep 18.PMID: 14500548 [PubMed - indexed for MEDLINE]Related articlesFree article

Adaptation to hyperglycemia enhances insulin secretion in glucokinase mutant mice.

Sreenan SK, Cockburn BN, Baldwin AC, Ostrega DM, Levisetti M, Grupe A, Bell GI, Stewart TA, Roe MW, Polonsky KS.

Diabetes. 1998 Dec;47(12):1881-8.PMID: 9836519 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of increased glucokinase gene copy number on glucose homeostasis and hepatic glucose metabolism.

Niswender KD, Shiota M, Postic C, Cherrington AD, Magnuson MA.

J Biol Chem. 1997 Sep 5;272(36):22570-5.PMID: 9278411 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of diabetes-related traits in MSM and JF1 mice on high-fat diet.

Kobayashi M, Ohno T, Tsuchiya T, Horio F.

J Nutr Biochem. 2004 Oct;15(10):614-21.PMID: 15542353 [PubMed - indexed for MEDLINE]Related articles

Glucokinase gene transfer to skeletal muscle of diabetic Zucker fatty rats improves insulin-sensitive glucose uptake.

Jiménez-Chillarón JC, Telemaque-Potts S, Gómez-Valadés AG, Anderson P, Newgard CB, Gómez-Foix AM.

Metabolism. 2002 Jan;51(1):121-6.PMID: 11782883 [PubMed - indexed for MEDLINE]Related articles

Diet differentially regulates glucokinase and L-type pyruvate kinase gene expression in rat liver.

Iritani N, Fukuda H, Tada K, Itoh A, Noguchi T.

J Nutr. 1995 Dec;125(12):2945-52.PMID: 7500172 [PubMed - indexed for MEDLINE]Related articlesFree article

Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele.

Rossetti L, Chen W, Hu M, Hawkins M, Barzilai N, Efrat S.

Am J Physiol. 1997 Oct;273(4 Pt 1):E743-50.PMID: 9357804 [PubMed - indexed for MEDLINE]Related articlesFree article

Mice mutant for glucokinase regulatory protein exhibit decreased liver glucokinase: a sequestration mechanism in metabolic regulation.

Farrelly D, Brown KS, Tieman A, Ren J, Lira SA, Hagan D, Gregg R, Mookhtiar KA, Hariharan N.

Proc Natl Acad Sci U S A. 1999 Dec 7;96(25):14511-6.PMID: 10588736 [PubMed - indexed for MEDLINE]Related articlesFree article

Adipogenic capacity and the susceptibility to type 2 diabetes and metabolic syndrome.

Wang MY, Grayburn P, Chen S, Ravazzola M, Orci L, Unger RH.

Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6139-44. Epub 2008 Apr 14.PMID: 18413598 [PubMed - indexed for MEDLINE]Related articlesFree article

Improved metabolic disorders of insulin receptor-deficient mice by transgenic overexpression of glucokinase in the liver.

Jackerott M, Baudry A, Bucchini D, Jami J, Joshi RL.

Diabetologia. 2002 Sep;45(9):1292-7. Epub 2002 Jul 31.PMID: 12242462 [PubMed - indexed for MEDLINE]Related articles

Dual roles for glucokinase in glucose homeostasis as determined by liver and pancreatic beta cell-specific gene knock-outs using Cre recombinase.

Postic C, Shiota M, Niswender KD, Jetton TL, Chen Y, Moates JM, Shelton KD, Lindner J, Cherrington AD, Magnuson MA.

J Biol Chem. 1999 Jan 1;274(1):305-15.PMID: 9867845 [PubMed - indexed for MEDLINE]Related articlesFree article

Cell-specific roles of glucokinase in glucose homeostasis.

Postic C, Shiota M, Magnuson MA.

Recent Prog Horm Res. 2001;56:195-217. Review.PMID: 11237213 [PubMed - indexed for MEDLINE]Related articlesFree article

High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI. Diabetes Study Group of the Italian Society of Paediatric Endocrinology and Diabetes (SIEDP).

Massa O, Meschi F, Cuesta-Munoz A, Caumo A, Cerutti F, Toni S, Cherubini V, Guazzarotti L, Sulli N, Matschinsky FM, Lorini R, Iafusco D, Barbetti F; Italian Society of Paediatic Endocrinology and Diabetes (SIEDP).

Diabetologia. 2001 Jul;44(7):898-905.PMID: 11508276 [PubMed - indexed for MEDLINE]Related articles

Expression of glucokinase in skeletal muscle: a new approach to counteract diabetic hyperglycemia.

Otaegui PJ, Ferre T, Pujol A, Riu E, Jimenez R, Bosch F.

Hum Gene Ther. 2000 Jul 20;11(11):1543-52.PMID: 10945768 [PubMed - indexed for MEDLINE]Related articles

Intraperitoneal PACAP administration decreases blood glucose in GK rats, and in normal and high fat diet mice.

Yada T, Sakurada M, Filipsson K, Kikuchi M, Ahrén B.

Ann N Y Acad Sci. 2000;921:259-63.PMID: 11193831 [PubMed - indexed for MEDLINE]Related articles