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    Results: 1 to 20 of 153

    1.

    Distinction between interleukin-1-induced necrosis and apoptosis of islet cells.

    Hoorens A, Stangé G, Pavlovic D, Pipeleers D.

    Diabetes. 2001 Mar;50(3):551-7.PMID: 11246874 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Interleukin-1beta-induced alteration in a beta-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis.

    Ling Z, Van de Casteele M, Eizirik DL, Pipeleers DG.

    Diabetes. 2000 Mar;49(3):340-5.PMID: 10868954 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Double-stranded ribonucleic acid (RNA) induces beta-cell Fas messenger RNA expression and increases cytokine-induced beta-cell apoptosis.

    Liu D, Darville M, Eizirik DL.

    Endocrinology. 2001 Jun;142(6):2593-9.PMID: 11356709 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Suppressor of cytokine signaling 3 (SOCS-3) protects beta -cells against interleukin-1beta - and interferon-gamma -mediated toxicity.

    Karlsen AE, Rønn SG, Lindberg K, Johannesen J, Galsgaard ED, Pociot F, Nielsen JH, Mandrup-Poulsen T, Nerup J, Billestrup N.

    Proc Natl Acad Sci U S A. 2001 Oct 9;98(21):12191-6. Epub 2001 Oct 2.PMID: 11593036 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Insulin-like growth factors prevent cytokine-mediated cell death in isolated islets of Langerhans from pre-diabetic non-obese diabetic mice.

    Hill DJ, Petrik J, Arany E, McDonald TJ, Delovitch TL.

    J Endocrinol. 1999 Apr;161(1):153-65.PMID: 10194539 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Interleukin-18 mRNA, but not interleukin-18 receptor mRNA, is constitutively expressed in islet beta-cells and up-regulated by interferon-gamma.

    Hong TP, Andersen NA, Nielsen K, Karlsen AE, Fantuzzi G, Eizirik DL, Dinarello CA, Mandrup-Poulsen T.

    Eur Cytokine Netw. 2000 Jun;11(2):193-205.PMID: 10903798 [PubMed - indexed for MEDLINE]Related articles

    7.

    STAT5 activation by human GH protects insulin-producing cells against interleukin-1beta, interferon-gamma and tumour necrosis factor-alpha-induced apoptosis independent of nitric oxide production.

    Jensen J, Galsgaard ED, Karlsen AE, Lee YC, Nielsen JH.

    J Endocrinol. 2005 Oct;187(1):25-36.PMID: 16214938 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling.

    Ling Z, Van de Casteele M, Dong J, Heimberg H, Haefliger JA, Waeber G, Schuit F, Pipeleers D.

    Diabetes. 2003 Oct;52(10):2497-502.PMID: 14514632 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Mechanisms of beta-cell death in response to double-stranded (ds) RNA and interferon-gamma: dsRNA-dependent protein kinase apoptosis and nitric oxide-dependent necrosis.

    Scarim AL, Arnush M, Blair LA, Concepcion J, Heitmeier MR, Scheuner D, Kaufman RJ, Ryerse J, Buller RM, Corbett JA.

    Am J Pathol. 2001 Jul;159(1):273-83.PMID: 11438474 [PubMed - indexed for MEDLINE]Related articlesFree article

    10.

    Role of p38 mitogen-activated protein kinase (p38 MAPK) in cytokine-induced rat islet cell apoptosis.

    Saldeen J, Lee JC, Welsh N.

    Biochem Pharmacol. 2001 Jun 15;61(12):1561-9.PMID: 11377386 [PubMed - indexed for MEDLINE]Related articles

    11.

    Interleukin (IL)-1beta toxicity to islet beta cells: Efaroxan exerts a complete protection.

    Papaccio G, Graziano A, Valiante S, D'Aquino R, Travali S, Nicoletti F.

    J Cell Physiol. 2005 Apr;203(1):94-102.PMID: 15389634 [PubMed - indexed for MEDLINE]Related articles

    12.

    High glucose potentiates cytokine- and streptozotocin-induced apoptosis of rat islet cells: effect on apoptosis-related genes.

    Mellado-Gil JM, Aguilar-Diosdado M.

    J Endocrinol. 2004 Oct;183(1):155-62.PMID: 15525583 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Double-stranded RNA cooperates with interferon-gamma and IL-1 beta to induce both chemokine expression and nuclear factor-kappa B-dependent apoptosis in pancreatic beta-cells: potential mechanisms for viral-induced insulitis and beta-cell death in type 1 diabetes mellitus.

    Liu D, Cardozo AK, Darville MI, Eizirik DL.

    Endocrinology. 2002 Apr;143(4):1225-34.PMID: 11897677 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Cytokine-induced beta-cell apoptosis is NO-dependent, mitochondria-mediated and inhibited by BCL-XL.

    Holohan C, Szegezdi E, Ritter T, O'Brien T, Samali A.

    J Cell Mol Med. 2008 Apr;12(2):591-606. Epub 2007 Dec 10.PMID: 18081694 [PubMed - indexed for MEDLINE]Related articles

    15.

    Monocyte chemoattractant protein-1 is expressed in pancreatic islets from prediabetic NOD mice and in interleukin-1 beta-exposed human and rat islet cells.

    Chen MC, Proost P, Gysemans C, Mathieu C, Eizirik DL.

    Diabetologia. 2001 Mar;44(3):325-32.PMID: 11317664 [PubMed - indexed for MEDLINE]Related articles

    16.

    Comparison of cellular and medium insulin and GABA content as markers for living beta-cells.

    Wang C, Ling Z, Pipeleers D.

    Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E307-13. Epub 2004 Sep 28.PMID: 15454397 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    IL-1beta, IFN-gamma and TNF-alpha increase vulnerability of pancreatic beta cells to autoimmune destruction.

    Wachlin G, Augstein P, Schröder D, Kuttler B, Klöting I, Heinke P, Schmidt S.

    J Autoimmun. 2003 Jun;20(4):303-12.PMID: 12791316 [PubMed - indexed for MEDLINE]Related articles

    18.

    Interleukin-1 plus gamma-interferon-induced pancreatic beta-cell dysfunction is mediated by beta-cell nitric oxide production.

    Thomas HE, Darwiche R, Corbett JA, Kay TW.

    Diabetes. 2002 Feb;51(2):311-6.PMID: 11812737 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Complete protection against interleukin-1beta-induced functional suppression and cytokine-mediated cytotoxicity in rat pancreatic islets in vitro using an interleukin-1 cytokine trap.

    Rydgren T, Bengtsson D, Sandler S.

    Diabetes. 2006 May;55(5):1407-12.PMID: 16644698 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis.

    Hoorens A, Pipeleers D.

    Diabetologia. 1999 Jan;42(1):55-9.PMID: 10027579 [PubMed - indexed for MEDLINE]Related articles

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