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Measurements of cytoplasmic Ca2+ in islet cell clusters show that glucose rapidly recruits beta-cells and gradually increases the individual cell response.
Jonkers FC, Henquin JC.
Diabetes. 2001 Mar;50(3):540-50.PMID: 11246873 [PubMed - indexed for MEDLINE]Related articlesFree article
Tolbutamide stimulation of pancreatic beta-cells involves both cell recruitment and increase in the individual Ca(2+) response.
Jonkers FC, Guiot Y, Rahier J, Henquin JC.
Br J Pharmacol. 2001 Jun;133(4):575-85.PMID: 11399675 [PubMed - indexed for MEDLINE]Related articlesFree article
Temporal and quantitative correlations between insulin secretion and stably elevated or oscillatory cytoplasmic Ca2+ in mouse pancreatic beta-cells.
Jonas JC, Gilon P, Henquin JC.
Diabetes. 1998 Aug;47(8):1266-73.PMID: 9703327 [PubMed - indexed for MEDLINE]Related articlesFree article
Tolbutamide and diazoxide influence insulin secretion by changing the concentration but not the action of cytoplasmic Ca2+ in beta-cells.
Mariot P, Gilon P, Nenquin M, Henquin JC.
Diabetes. 1998 Mar;47(3):365-73.PMID: 9519741 [PubMed - indexed for MEDLINE]Related articlesFree article
Identification of alpha- and beta-cells in intact isolated islets of Langerhans by their characteristic cytoplasmic Ca2+ concentration dynamics and immunocytochemical staining.
Asada N, Shibuya I, Iwanaga T, Niwa K, Kanno T.
Diabetes. 1998 May;47(5):751-7.PMID: 9588446 [PubMed - indexed for MEDLINE]Related articlesFree article
Distinct effects of glucose on the synchronous oscillations of insulin release and cytoplasmic Ca2+ concentration measured simultaneously in single mouse islets.
Gilon P, Henquin JC.
Endocrinology. 1995 Dec;136(12):5725-30.PMID: 7588329 [PubMed - indexed for MEDLINE]Related articles
Glucose-stimulated elevation of cytoplasmic calcium is defective in the diabetic Chinese hamster islet B cell.
Lindström P, Sehlin J, Frankel BJ.
Eur J Endocrinol. 1996 May;134(5):617-25.PMID: 8664983 [PubMed - indexed for MEDLINE]Related articles
Influence of cell number on the characteristics and synchrony of Ca2+ oscillations in clusters of mouse pancreatic islet cells.
Jonkers FC, Jonas JC, Gilon P, Henquin JC.
J Physiol. 1999 Nov 1;520 Pt 3:839-49.PMID: 10545148 [PubMed - indexed for MEDLINE]Related articlesFree article
Alterations of insulin secretion from mouse islets treated with sulphonylureas: perturbations of Ca2+ regulation prevail over changes in insulin content.
Anello M, Gilon P, Henquin JC.
Br J Pharmacol. 1999 Aug;127(8):1883-91.PMID: 10482920 [PubMed - indexed for MEDLINE]Related articlesFree article
Insulin secretagogues, but not glucose, stimulate an increase in [Ca2+]i in the fetal rat beta-cell.
Weinhaus AJ, Poronnik P, Cook DI, Tuch BE.
Diabetes. 1995 Jan;44(1):118-24.PMID: 7529202 [PubMed - indexed for MEDLINE]Related articles
Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets.
Antunes CM, Salgado AP, Rosário LM, Santos RM.
Diabetes. 2000 Dec;49(12):2028-38.PMID: 11118004 [PubMed - indexed for MEDLINE]Related articlesFree article
Triggering and amplifying pathways of regulation of insulin secretion by glucose.
Henquin JC.
Diabetes. 2000 Nov;49(11):1751-60. Review.PMID: 11078440 [PubMed - indexed for MEDLINE]Related articlesFree article
Glucose-induced pulsatile insulin release from single islets at stable and oscillatory cytoplasmic Ca2+.
Bergsten P.
Am J Physiol. 1998 May;274(5 Pt 1):E796-800.PMID: 9612236 [PubMed - indexed for MEDLINE]Related articlesFree article
Significance of the calcium content of mouse beta cells in the preservation of glucose-induced insulin release during culture.
J Endocrinol. 1987 Oct;115(1):27-34.PMID: 3312466 [PubMed - indexed for MEDLINE]Related articles
Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet beta-cells.
Yada T, Nakata M, Shiraishi T, Kakei M.
Br J Pharmacol. 1999 Mar;126(5):1205-13.PMID: 10205010 [PubMed - indexed for MEDLINE]Related articlesFree article
In vivo and in vitro glucose-induced biphasic insulin secretion in the mouse: pattern and role of cytoplasmic Ca2+ and amplification signals in beta-cells.
Henquin JC, Nenquin M, Stiernet P, Ahren B.
Diabetes. 2006 Feb;55(2):441-51.PMID: 16443779 [PubMed - indexed for MEDLINE]Related articlesFree article
Energetic requirement of insulin secretion distal to calcium influx.
Rustenbeck I, Herrmann C, Grimmsmann T.
Diabetes. 1997 Aug;46(8):1305-11.PMID: 9231655 [PubMed - indexed for MEDLINE]Related articles
Insulin exocytosis and glucose-mediated increase in cytoplasmic free Ca2+ concentration in the pancreatic beta-cell are independent of cyclic ADP-ribose.
Webb DL, Islam MS, Efanov AM, Brown G, Köhler M, Larsson O, Berggren PO.
J Biol Chem. 1996 Aug 9;271(32):19074-9.PMID: 8702579 [PubMed - indexed for MEDLINE]Related articlesFree article
Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance.
Kindmark H, Köhler M, Arkhammar P, Efendic S, Larsson O, Linder S, Nilsson T, Berggren PO.
Diabetologia. 1994 Nov;37(11):1121-31.PMID: 7867884 [PubMed - indexed for MEDLINE]Related articles
Glucose regulation of glutaminolysis and its role in insulin secretion.
Gao ZY, Li G, Najafi H, Wolf BA, Matschinsky FM.
Diabetes. 1999 Aug;48(8):1535-42.PMID: 10426370 [PubMed - indexed for MEDLINE]Related articlesFree article
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