PubMed

Efficient ex vivo transduction of pancreatic islet cells with recombinant adeno-associated virus vectors.

Flotte T, Agarwal A, Wang J, Song S, Fenjves ES, Inverardi L, Chesnut K, Afione S, Loiler S, Wasserfall C, Kapturczak M, Ellis T, Nick H, Atkinson M.

Diabetes. 2001 Mar;50(3):515-20.PMID: 11246870 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus (AAV) as a vehicle for therapeutic gene delivery: improvements in vector design and viral production enhance potential to prolong graft survival in pancreatic islet cell transplantation for the reversal of type 1 diabetes.

Kapturczak MH, Flotte T, Atkinson MA.

Curr Mol Med. 2001 May;1(2):245-58. Review.PMID: 11899074 [PubMed - indexed for MEDLINE]Related articles

Transduction of human and mouse pancreatic islet cells using a bicistronic recombinant adeno-associated viral vector.

Kapturczak M, Zolotukhin S, Cross J, Pileggi A, Molano RD, Jorgensen M, Byrne B, Flotte TR, Ellis T, Inverardi L, Ricordi C, Nick H, Atkinson M, Agarwal A.

Mol Ther. 2002 Feb;5(2):154-60.PMID: 11829522 [PubMed - indexed for MEDLINE]Related articlesFree article

Adeno-associated virus vector mediated gene transfer to pancreatic beta cells.

Prasad KM, Yang Z, Bleich D, Nadler JL.

Gene Ther. 2000 Sep;7(18):1553-61.PMID: 11021593 [PubMed - indexed for MEDLINE]Related articlesFree article

Glucose-modulated transgene expression via recombinant adeno-associated virus.

Yang YW, Hsieh YC, Chao CK.

Pharm Res. 2002 Jul;19(7):968-75.PMID: 12180549 [PubMed - indexed for MEDLINE]Related articles

Transduction of pancreatic islets with pseudotyped adeno-associated virus: effect of viral capsid and genome conversion.

Zhang N, Clément N, Chen D, Fu S, Zhang H, Rebollo P, Linden RM, Bromberg JS.

Transplantation. 2005 Sep 15;80(5):683-90.PMID: 16177645 [PubMed - indexed for MEDLINE]Related articles

Adeno-associated virus-mediated IL-10 gene therapy inhibits diabetes recurrence in syngeneic islet cell transplantation of NOD mice.

Zhang YC, Pileggi A, Agarwal A, Molano RD, Powers M, Brusko T, Wasserfall C, Goudy K, Zahr E, Poggioli R, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Nick H, Flotte T, Ellis TM, Ricordi C, Inverardi L, Atkinson MA.

Diabetes. 2003 Mar;52(3):708-16.PMID: 12606512 [PubMed - indexed for MEDLINE]Related articlesFree article

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.

Kuttler B, Wanka H, Klöting N, Gerstmayer B, Volk HD, Sawitzki B, Ritter T.

J Cell Mol Med. 2007 Jul-Aug;11(4):868-80.PMID: 17760846 [PubMed - indexed for MEDLINE]Related articles

Lentivirus-mediated transduction of islet grafts with interleukin 4 results in sustained gene expression and protection from insulitis.

Gallichan WS, Kafri T, Krahl T, Verma IM, Sarvetnick N.

Hum Gene Ther. 1998 Dec 10;9(18):2717-26.PMID: 9874270 [PubMed - indexed for MEDLINE]Related articles

Double genetic modification of adenovirus fiber with RGD polylysine motifs significantly enhances gene transfer to isolated human pancreatic islets.

Contreras JL, Wu H, Smyth CA, Eckstein CP, Young CJ, Seki T, Bilbao G, Curiel DT, Eckhoff DE.

Transplantation. 2003 Jul 15;76(1):252-61.PMID: 12865820 [PubMed - indexed for MEDLINE]Related articles

Adeno-associated virus transduction of islets with interleukin-4 results in impaired metabolic function in syngeneic marginal islet mass transplantation.

Zhang YC, Molano RD, Pileggi A, Powers M, Cross J, Wasserfall C, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Flotte T, Ellis TM, Ricordi C, Atkinson MA, Inverardi L.

Transplantation. 2002 Oct 27;74(8):1184-6.PMID: 12438968 [PubMed - indexed for MEDLINE]Related articles

Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice.

Smith DK, Korbutt GS, Suarez-Pinzon WL, Kao D, Rajotte RV, Elliott JF.

Transplantation. 1997 Oct 15;64(7):1040-9.PMID: 9381527 [PubMed - indexed for MEDLINE]Related articles

Glucose-responsive gene delivery in pancreatic Islet cells via recombinant adeno-associated viral vectors.

Yang YW, Kotin RM.

Pharm Res. 2000 Sep;17(9):1056-61.PMID: 11087036 [PubMed - indexed for MEDLINE]Related articles

Immunity to islet grafts transduced with adenovirus vectors does not inhibit long-term islet function.

Cheng J, Sun J, Sung RS.

Transpl Immunol. 2009 May;21(1):33-42. Epub 2009 Feb 15.PMID: 19224710 [PubMed - indexed for MEDLINE]Related articles

Long-term gene expression and metabolic control exerted by lentivirus-transduced pancreatic islets.

He Z, Wang F, Kumagai-Braesch M, Permert J, Holgersson J.

Xenotransplantation. 2006 May;13(3):195-203.PMID: 16756562 [PubMed - indexed for MEDLINE]Related articles

Comparison of adenoviral and adeno-associated viral vectors for pancreatic gene delivery in vivo.

Wang AY, Peng PD, Ehrhardt A, Storm TA, Kay MA.

Hum Gene Ther. 2004 Apr;15(4):405-13.PMID: 15053865 [PubMed - indexed for MEDLINE]Related articles

Genetically modified adenovirus vector containing an RGD peptide in the HI loop of the fiber knob improves gene transfer to nonhuman primate isolated pancreatic islets.

Bilbao G, Contreras JL, Dmitriev I, Smyth CA, Jenkins S, Eckhoff D, Thomas F, Thomas J, Curiel DT.

Am J Transplant. 2002 Mar;2(3):237-43.PMID: 12096786 [PubMed - indexed for MEDLINE]Related articles

Adeno-associated virus vector-mediated IL-10 gene delivery prevents type 1 diabetes in NOD mice.

Goudy K, Song S, Wasserfall C, Zhang YC, Kapturczak M, Muir A, Powers M, Scott-Jorgensen M, Campbell-Thompson M, Crawford JM, Ellis TM, Flotte TR, Atkinson MA.

Proc Natl Acad Sci U S A. 2001 Nov 20;98(24):13913-8.PMID: 11717448 [PubMed - indexed for MEDLINE]Related articlesFree article

Systemic overexpression of IL-10 induces CD4+CD25+ cell populations in vivo and ameliorates type 1 diabetes in nonobese diabetic mice in a dose-dependent fashion.

Goudy KS, Burkhardt BR, Wasserfall C, Song S, Campbell-Thompson ML, Brusko T, Powers MA, Clare-Salzler MJ, Sobel ES, Ellis TM, Flotte TR, Atkinson MA.

J Immunol. 2003 Sep 1;171(5):2270-8.PMID: 12928371 [PubMed - indexed for MEDLINE]Related articlesFree article

Targeting recombinant adeno-associated virus vectors to enhance gene transfer to pancreatic islets and liver.

Loiler SA, Conlon TJ, Song S, Tang Q, Warrington KH, Agarwal A, Kapturczak M, Li C, Ricordi C, Atkinson MA, Muzyczka N, Flotte TR.

Gene Ther. 2003 Sep;10(18):1551-8.PMID: 12907946 [PubMed - indexed for MEDLINE]Related articles