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    Results: 1 to 20 of 191

    1.

    Decreased in situ insulin receptor dephosphorylation in hyperglycemia-induced insulin resistance in rat adipocytes.

    Tang S, Le-Tien H, Goldstein BJ, Shin P, Lai R, Fantus IG.

    Diabetes. 2001 Jan;50(1):83-90.PMID: 11147799 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Hyperglycemia potentiates H(2)O(2) production in adipocytes and enhances insulin signal transduction: potential role for oxidative inhibition of thiol-sensitive protein-tyrosine phosphatases.

    Wu X, Zhu L, Zilbering A, Mahadev K, Motoshima H, Yao J, Goldstein BJ.

    Antioxid Redox Signal. 2005 May-Jun;7(5-6):526-37.PMID: 15889998 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    Reciprocal feedback regulation of insulin receptor and insulin receptor substrate tyrosine phosphorylation by phosphoinositide 3-kinase in primary adipocytes.

    Hers I, Bell CJ, Poole AW, Jiang D, Denton RM, Schaefer E, Tavaré JM.

    Biochem J. 2002 Dec 15;368(Pt 3):875-84.PMID: 12220227 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Enhanced sensitivity of insulin-resistant adipocytes to vanadate is associated with oxidative stress and decreased reduction of vanadate (+5) to vanadyl (+4).

    Lu B, Ennis D, Lai R, Bogdanovic E, Nikolov R, Salamon L, Fantus C, Le-Tien H, Fantus IG.

    J Biol Chem. 2001 Sep 21;276(38):35589-98. Epub 2001 Jul 19.PMID: 11463798 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase.

    Cheung AT, Wang J, Ree D, Kolls JK, Bryer-Ash M.

    Diabetes. 2000 May;49(5):810-9.PMID: 10905491 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Dynamics of protein-tyrosine phosphatases in rat adipocytes.

    Calera MR, Vallega G, Pilch PF.

    J Biol Chem. 2000 Mar 3;275(9):6308-12.PMID: 10692429 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Tyrosine dephosphorylation and deactivation of insulin receptor substrate-1 by protein-tyrosine phosphatase 1B. Possible facilitation by the formation of a ternary complex with the Grb2 adaptor protein.

    Goldstein BJ, Bittner-Kowalczyk A, White MF, Harbeck M.

    J Biol Chem. 2000 Feb 11;275(6):4283-9.PMID: 10660596 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Transgenic overexpression of protein-tyrosine phosphatase 1B in muscle causes insulin resistance, but overexpression with leukocyte antigen-related phosphatase does not additively impair insulin action.

    Zabolotny JM, Haj FG, Kim YB, Kim HJ, Shulman GI, Kim JK, Neel BG, Kahn BB.

    J Biol Chem. 2004 Jun 4;279(23):24844-51. Epub 2004 Mar 18.PMID: 15031294 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Receptor-type protein tyrosine phosphatase epsilon (PTPepsilonM) is a negative regulator of insulin signaling in primary hepatocytes and liver.

    Nakagawa Y, Aoki N, Aoyama K, Shimizu H, Shimano H, Yamada N, Miyazaki H.

    Zoolog Sci. 2005 Feb;22(2):169-75.PMID: 15738637 [PubMed - indexed for MEDLINE]Related articles

    10.

    Insulin resistance induced by tumor necrosis factor-alpha in myocytes and brown adipocytes.

    Lorenzo M, Fernández-Veledo S, Vila-Bedmar R, Garcia-Guerra L, De Alvaro C, Nieto-Vazquez I.

    J Anim Sci. 2008 Apr;86(14 Suppl):E94-104. Epub 2007 Oct 16. Review.PMID: 17940160 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Dephosphorylation of insulin receptor substrate 1 by the tyrosine phosphatase PTP2C.

    Kuhné MR, Zhao Z, Rowles J, Lavan BE, Shen SH, Fischer EH, Lienhard GE.

    J Biol Chem. 1994 Jun 3;269(22):15833-7.PMID: 7515062 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.

    Mur C, Valverde AM, Kahn CR, Benito M.

    Diabetes. 2002 Mar;51(3):743-54.PMID: 11872675 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    The dephosphorylation of insulin and epidermal growth factor receptors. Role of endosome-associated phosphotyrosine phosphatase(s).

    Faure R, Baquiran G, Bergeron JJ, Posner BI.

    J Biol Chem. 1992 Jun 5;267(16):11215-21.PMID: 1375938 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    A role for tyrosine phosphorylation in both activation and inhibition of the insulin receptor tyrosine kinase in vivo.

    Drake PG, Bevan AP, Burgess JW, Bergeron JJ, Posner BI.

    Endocrinology. 1996 Nov;137(11):4960-8.PMID: 8895369 [PubMed - indexed for MEDLINE]Related articles

    15.

    Small molecule peptidomimetics containing a novel phosphotyrosine bioisostere inhibit protein tyrosine phosphatase 1B and augment insulin action.

    Bleasdale JE, Ogg D, Palazuk BJ, Jacob CS, Swanson ML, Wang XY, Thompson DP, Conradi RA, Mathews WR, Laborde AL, Stuchly CW, Heijbel A, Bergdahl K, Bannow CA, Smith CW, Svensson C, Liljebris C, Schostarez HJ, May PD, Stevens FC, Larsen SD.

    Biochemistry. 2001 May 15;40(19):5642-54.PMID: 11341829 [PubMed - indexed for MEDLINE]Related articles

    16.

    Pioglitazone ameliorates tumor necrosis factor-alpha-induced insulin resistance by a mechanism independent of adipogenic activity of peroxisome proliferator--activated receptor-gamma.

    Iwata M, Haruta T, Usui I, Takata Y, Takano A, Uno T, Kawahara J, Ueno E, Sasaoka T, Ishibashi O, Kobayashi M.

    Diabetes. 2001 May;50(5):1083-92.PMID: 11334412 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Overexpression of the LAR (leukocyte antigen-related) protein-tyrosine phosphatase in muscle causes insulin resistance.

    Zabolotny JM, Kim YB, Peroni OD, Kim JK, Pani MA, Boss O, Klaman LD, Kamatkar S, Shulman GI, Kahn BB, Neel BG.

    Proc Natl Acad Sci U S A. 2001 Apr 24;98(9):5187-92. Epub 2001 Apr 17.PMID: 11309481 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Differential dephosphorylation of the insulin receptor and its 160-kDa substrate (pp160) in rat adipocytes.

    Mooney RA, Bordwell KL.

    J Biol Chem. 1992 Jul 15;267(20):14054-60.PMID: 1321133 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Insulin receptor dephosphorylation in permeabilized adipocytes is inhibitable by manganese and independent of receptor kinase activity.

    Mooney RA, Green DA.

    Biochem Biophys Res Commun. 1989 Aug 15;162(3):1200-6.PMID: 2475105 [PubMed - indexed for MEDLINE]Related articles

    20.

    High glucose and insulin in combination cause insulin receptor substrate-1 and -2 depletion and protein kinase B desensitisation in primary cultured rat adipocytes: possible implications for insulin resistance in type 2 diabetes.

    Burén J, Liu HX, Lauritz J, Eriksson JW.

    Eur J Endocrinol. 2003 Jan;148(1):157-67.PMID: 12534369 [PubMed - indexed for MEDLINE]Related articlesFree article

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