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    Results: 1 to 20 of 121

    1.

    Cell-permeable peptide inhibitors of JNK: novel blockers of beta-cell death.

    Bonny C, Oberson A, Negri S, Sauser C, Schorderet DF.

    Diabetes. 2001 Jan;50(1):77-82.PMID: 11147798 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    The c-Jun amino-terminal kinase pathway is preferentially activated by interleukin-1 and controls apoptosis in differentiating pancreatic beta-cells.

    Ammendrup A, Maillard A, Nielsen K, Aabenhus Andersen N, Serup P, Dragsbaek Madsen O, Mandrup-Poulsen T, Bonny C.

    Diabetes. 2000 Sep;49(9):1468-76.PMID: 10969830 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    The JNK binding domain of islet-brain 1 inhibits IL-1 induced JNK activity and apoptosis but not the transcription of key proapoptotic or protective genes in insulin-secreting cell lines.

    Nikulina MA, Sandhu N, Shamim Z, Andersen NA, Oberson A, Dupraz P, Thorens B, Karlsen AE, Bonny C, Mandrup-Poulsen T.

    Cytokine. 2003 Oct;24(1-2):13-24.PMID: 14561487 [PubMed - indexed for MEDLINE]Related articles

    4.

    The c-Jun N-terminal kinase JNK participates in cytokine- and isolation stress-induced rat pancreatic islet apoptosis.

    Abdelli S, Abderrahmani A, Hering BJ, Beckmann JS, Bonny C.

    Diabetologia. 2007 Aug;50(8):1660-9. Epub 2007 Jun 9.PMID: 17558486 [PubMed - indexed for MEDLINE]Related articles

    5.

    The scaffold protein IB1/JIP-1 is a critical mediator of cytokine-induced apoptosis in pancreatic beta cells.

    Haefliger JA, Tawadros T, Meylan L, Gurun SL, Roehrich ME, Martin D, Thorens B, Waeber G.

    J Cell Sci. 2003 Apr 15;116(Pt 8):1463-9.PMID: 12640031 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    Variations in IB1/JIP1 expression regulate susceptibility of beta-cells to cytokine-induced apoptosis irrespective of C-Jun NH2-terminal kinase signaling.

    Ling Z, Van de Casteele M, Dong J, Heimberg H, Haefliger JA, Waeber G, Schuit F, Pipeleers D.

    Diabetes. 2003 Oct;52(10):2497-502.PMID: 14514632 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    cDNA cloning and mapping of a novel islet-brain/JNK-interacting protein.

    Negri S, Oberson A, Steinmann M, Sauser C, Nicod P, Waeber G, Schorderet DF, Bonny C.

    Genomics. 2000 Mar 15;64(3):324-30.PMID: 10756100 [PubMed - indexed for MEDLINE]Related articles

    8.

    Calcium has a permissive role in interleukin-1beta-induced c-jun N-terminal kinase activation in insulin-secreting cells.

    Størling J, Zaitsev SV, Kapelioukh IL, Karlsen AE, Billestrup N, Berggren PO, Mandrup-Poulsen T.

    Endocrinology. 2005 Jul;146(7):3026-36. Epub 2005 Apr 14.PMID: 15831571 [PubMed - indexed for MEDLINE]Related articlesFree article

    9.

    Suppression of the c-Jun N-terminal kinase pathway by 17beta-estradiol can preserve human islet functional mass from proinflammatory cytokine-induced destruction.

    Eckhoff DE, Smyth CA, Eckstein C, Bilbao G, Young CJ, Thompson JA, Contreras JL.

    Surgery. 2003 Aug;134(2):169-79.PMID: 12947315 [PubMed - indexed for MEDLINE]Related articles

    10.

    Exendin-4 protects beta-cells from interleukin-1 beta-induced apoptosis by interfering with the c-Jun NH2-terminal kinase pathway.

    Ferdaoussi M, Abdelli S, Yang JY, Cornu M, Niederhauser G, Favre D, Widmann C, Regazzi R, Thorens B, Waeber G, Abderrahmani A.

    Diabetes. 2008 May;57(5):1205-15. Epub 2008 Feb 5.PMID: 18252896 [PubMed - indexed for MEDLINE]Related articlesFree article

    11.

    Disruption of the c-JUN-JNK complex by a cell-permeable peptide containing the c-JUN delta domain induces apoptosis and affects a distinct set of interleukin-1-induced inflammatory genes.

    Holzberg D, Knight CG, Dittrich-Breiholz O, Schneider H, Dörrie A, Hoffmann E, Resch K, Kracht M.

    J Biol Chem. 2003 Oct 10;278(41):40213-23. Epub 2003 Jun 27.PMID: 12832416 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    Interleukin-1beta stimulation of c-Jun NH(2)-terminal kinase activity in insulin-secreting cells: evidence for cytoplasmic restriction.

    Major CD, Wolf BA.

    Diabetes. 2001 Dec;50(12):2721-8.PMID: 11723054 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Silymarin protects pancreatic beta-cells against cytokine-mediated toxicity: implication of c-Jun NH2-terminal kinase and janus kinase/signal transducer and activator of transcription pathways.

    Matsuda T, Ferreri K, Todorov I, Kuroda Y, Smith CV, Kandeel F, Mullen Y.

    Endocrinology. 2005 Jan;146(1):175-85. Epub 2004 Sep 30.PMID: 15459112 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The pro-atherogenic cytokine interleukin-18 induces CXCL16 expression in rat aortic smooth muscle cells via MyD88, interleukin-1 receptor-associated kinase, tumor necrosis factor receptor-associated factor 6, c-Src, phosphatidylinositol 3-kinase, Akt, c-Jun N-terminal kinase, and activator protein-1 signaling.

    Chandrasekar B, Mummidi S, Valente AJ, Patel DN, Bailey SR, Freeman GL, Hatano M, Tokuhisa T, Jensen LE.

    J Biol Chem. 2005 Jul 15;280(28):26263-77. Epub 2005 May 11.PMID: 15890643 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Cross-talk between phosphatidylinositol 3-kinase/AKT and c-jun NH2-terminal kinase mediates survival of isolated human islets.

    Aikin R, Maysinger D, Rosenberg L.

    Endocrinology. 2004 Oct;145(10):4522-31. Epub 2004 Jul 8.PMID: 15242986 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    A peptide inhibitor of c-Jun N-terminal kinase protects against both aminoglycoside and acoustic trauma-induced auditory hair cell death and hearing loss.

    Wang J, Van De Water TR, Bonny C, de Ribaupierre F, Puel JL, Zine A.

    J Neurosci. 2003 Sep 17;23(24):8596-607.PMID: 13679429 [PubMed - indexed for MEDLINE]Related articlesFree article

    17.

    Dexamethasone inhibits IL-12p40 production in lipopolysaccharide-stimulated human monocytic cells by down-regulating the activity of c-Jun N-terminal kinase, the activation protein-1, and NF-kappa B transcription factors.

    Ma W, Gee K, Lim W, Chambers K, Angel JB, Kozlowski M, Kumar A.

    J Immunol. 2004 Jan 1;172(1):318-30.PMID: 14688340 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Grape seed extract inhibits EGF-induced and constitutively active mitogenic signaling but activates JNK in human prostate carcinoma DU145 cells: possible role in antiproliferation and apoptosis.

    Tyagi A, Agarwal R, Agarwal C.

    Oncogene. 2003 Mar 6;22(9):1302-16.PMID: 12618755 [PubMed - indexed for MEDLINE]Related articles

    19.

    AMP-activated protein kinase can induce apoptosis of insulin-producing MIN6 cells through stimulation of c-Jun-N-terminal kinase.

    Kefas BA, Cai Y, Ling Z, Heimberg H, Hue L, Pipeleers D, Van de Casteele M.

    J Mol Endocrinol. 2003 Apr;30(2):151-61.PMID: 12683939 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Nitric oxide contributes to cytokine-induced apoptosis in pancreatic beta cells via potentiation of JNK activity and inhibition of Akt.

    Størling J, Binzer J, Andersson AK, Züllig RA, Tonnesen M, Lehmann R, Spinas GA, Sandler S, Billestrup N, Mandrup-Poulsen T.

    Diabetologia. 2005 Oct;48(10):2039-50. Epub 2005 Aug 25.PMID: 16132952 [PubMed - indexed for MEDLINE]Related articles

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