PubMed

A genetic defect in beta-cell gene expression segregates independently from the fa locus in the ZDF rat.

Griffen SC, Wang J, German MS.

Diabetes. 2001 Jan;50(1):63-8.PMID: 11147796 [PubMed - indexed for MEDLINE]Related articlesFree article

Antecedent hyperglycemia, not hyperlipidemia, is associated with increased islet triacylglycerol content and decreased insulin gene mRNA level in Zucker diabetic fatty rats.

Harmon JS, Gleason CE, Tanaka Y, Poitout V, Robertson RP.

Diabetes. 2001 Nov;50(11):2481-6.PMID: 11679425 [PubMed - indexed for MEDLINE]Related articlesFree article

Evolution of beta-cell dysfunction in the male Zucker diabetic fatty rat.

Tokuyama Y, Sturis J, DePaoli AM, Takeda J, Stoffel M, Tang J, Sun X, Polonsky KS, Bell GI.

Diabetes. 1995 Dec;44(12):1447-57.PMID: 7589853 [PubMed - indexed for MEDLINE]Related articles

Modulation of adipoinsular axis in prediabetic zucker diabetic fatty rats by diazoxide.

Alemzadeh R, Tushaus KM.

Endocrinology. 2004 Dec;145(12):5476-84. Epub 2004 Aug 19.PMID: 15319354 [PubMed - indexed for MEDLINE]Related articlesFree article

Overexpression of leptin receptors in pancreatic islets of Zucker diabetic fatty rats restores GLUT-2, glucokinase, and glucose-stimulated insulin secretion.

Wang MY, Koyama K, Shimabukuro M, Mangelsdorf D, Newgard CB, Unger RH.

Proc Natl Acad Sci U S A. 1998 Sep 29;95(20):11921-6.PMID: 9751766 [PubMed - indexed for MEDLINE]Related articlesFree article

Lipid-induced beta-cell dysfunction in vivo in models of progressive beta-cell failure.

Goh TT, Mason TM, Gupta N, So A, Lam TK, Lam L, Lewis GF, Mari A, Giacca A.

Am J Physiol Endocrinol Metab. 2007 Feb;292(2):E549-60. Epub 2006 Sep 26.PMID: 17003242 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective fatty acid-mediated beta-cell compensation in Zucker diabetic fatty rats. Pathogenic implications for obesity-dependent diabetes.

Hirose H, Lee YH, Inman LR, Nagasawa Y, Johnson JH, Unger RH.

J Biol Chem. 1996 Mar 8;271(10):5633-7.PMID: 8621426 [PubMed - indexed for MEDLINE]Related articlesFree article

Role of apoptosis in failure of beta-cell mass compensation for insulin resistance and beta-cell defects in the male Zucker diabetic fatty rat.

Pick A, Clark J, Kubstrup C, Levisetti M, Pugh W, Bonner-Weir S, Polonsky KS.

Diabetes. 1998 Mar;47(3):358-64.PMID: 9519740 [PubMed - indexed for MEDLINE]Related articlesFree article

Low mitochondrial glycerol phosphate dehydrogenase and pyruvate carboxylase in pancreatic islets of Zucker diabetic fatty rats.

MacDonald MJ, Tang J, Polonsky KS.

Diabetes. 1996 Nov;45(11):1626-30.PMID: 8866570 [PubMed - indexed for MEDLINE]Related articles

Limited role for SREBP-1c in defective glucose-induced insulin secretion from Zucker diabetic fatty rat islets: a functional and gene profiling analysis.

Parton LE, McMillen PJ, Shen Y, Docherty E, Sharpe E, Diraison F, Briscoe CP, Rutter GA.

Am J Physiol Endocrinol Metab. 2006 Nov;291(5):E982-94. Epub 2006 Jun 13.PMID: 16772326 [PubMed - indexed for MEDLINE]Related articlesFree article

Gene expression of mineralocorticoid and glucocorticoid receptors in the limbic system is related to type-2 like diabetes in leptin-resistant rats.

Jöhren O, Dendorfer A, Dominiak P, Raasch W.

Brain Res. 2007 Dec 12;1184:160-7. Epub 2007 Sep 22.PMID: 17945204 [PubMed - indexed for MEDLINE]Related articles

In vivo prevention of hyperglycemia also prevents glucotoxic effects on PDX-1 and insulin gene expression.

Harmon JS, Gleason CE, Tanaka Y, Oseid EA, Hunter-Berger KK, Robertson RP.

Diabetes. 1999 Oct;48(10):1995-2000.PMID: 10512364 [PubMed - indexed for MEDLINE]Related articlesFree article

Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats.

Lynn FC, Pamir N, Ng EH, McIntosh CH, Kieffer TJ, Pederson RA.

Diabetes. 2001 May;50(5):1004-11.PMID: 11334402 [PubMed - indexed for MEDLINE]Related articlesFree article

Effect of partial pancreatectomy on beta-cell mass in the remnant pancreas of Wistar fatty rats.

Ogino T, Zhu M, Murakami T, Kuwajima M, Shima K.

J Med Invest. 1998 Aug;45(1-4):103-10.PMID: 9864970 [PubMed - indexed for MEDLINE]Related articles

Islet microvasculature in islet hyperplasia and failure in a model of type 2 diabetes.

Li X, Zhang L, Meshinchi S, Dias-Leme C, Raffin D, Johnson JD, Treutelaar MK, Burant CF.

Diabetes. 2006 Nov;55(11):2965-73.PMID: 17065332 [PubMed - indexed for MEDLINE]Related articlesFree article

Fatty acid-induced beta cell apoptosis: a link between obesity and diabetes.

Shimabukuro M, Zhou YT, Levi M, Unger RH.

Proc Natl Acad Sci U S A. 1998 Mar 3;95(5):2498-502.PMID: 9482914 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced de novo lipogenesis in the leptin-unresponsive pancreatic islets of prediabetic Zucker diabetic fatty rats: role in the pathogenesis of lipotoxic diabetes.

Zhou YT, Shimabukuro M, Lee Y, Koyama K, Higa M, Ferguson T, Unger RH.

Diabetes. 1998 Dec;47(12):1904-8.PMID: 9836522 [PubMed - indexed for MEDLINE]Related articlesFree article

Oxidative stress induces p21 expression in pancreatic islet cells: possible implication in beta-cell dysfunction.

Kaneto H, Kajimoto Y, Fujitani Y, Matsuoka T, Sakamoto K, Matsuhisa M, Yamasaki Y, Hori M.

Diabetologia. 1999 Sep;42(9):1093-7.PMID: 10447521 [PubMed - indexed for MEDLINE]Related articles

Adenovirus-mediated overexpression of uncoupling protein-2 in pancreatic islets of Zucker diabetic rats increases oxidative activity and improves beta-cell function.

Wang MY, Shimabukuro M, Lee Y, Trinh KY, Chen JL, Newgard CB, Unger RH.

Diabetes. 1999 May;48(5):1020-5.PMID: 10331406 [PubMed - indexed for MEDLINE]Related articlesFree article

Analysis of gene expression profiles in insulin-sensitive tissues from pre-diabetic and diabetic Zucker diabetic fatty rats.

Suh YH, Kim Y, Bang JH, Choi KS, Lee JW, Kim WH, Oh TJ, An S, Jung MH.

J Mol Endocrinol. 2005 Apr;34(2):299-315.PMID: 15821098 [PubMed - indexed for MEDLINE]Related articlesFree article