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    Results: 1 to 20 of 166

    1.

    IGF-I mRNA and signaling in the diabetic retina.

    Gerhardinger C, McClure KD, Romeo G, Podestà F, Lorenzi M.

    Diabetes. 2001 Jan;50(1):175-83.PMID: 11147784 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Insulin-like growth factor-1-induced phosphorylation of transcription factor FKHRL1 is mediated by phosphatidylinositol 3-kinase/Akt kinase and role of this pathway in insulin-like growth factor-1-induced survival of cultured hippocampal neurons.

    Zheng WH, Kar S, Quirion R.

    Mol Pharmacol. 2002 Aug;62(2):225-33.PMID: 12130673 [PubMed - indexed for MEDLINE]Related articlesFree article

    3.

    PDGF- and insulin/IGF-1-specific distinct modes of class IA PI 3-kinase activation in normal rat retinas and RGC-5 retinal ganglion cells.

    Biswas SK, Zhao Y, Nagalingam A, Gardner TW, Sandirasegarane L.

    Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3687-98. Epub 2008 Apr 17.PMID: 18421086 [PubMed - indexed for MEDLINE]Related articlesFree article

    4.

    Des(1-3)IGF-1 treatment normalizes type 1 IGF receptor and phospho-Akt (Thr 308) immunoreactivity in predegenerative retina of diabetic rats.

    Kummer A, Pulford BE, Ishii DN, Seigel GM.

    Int J Exp Diabesity Res. 2003 Jan-Mar;4(1):45-57.PMID: 12745670 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Regulation of growth factor mRNA levels in the eyes of diabetic rats.

    Lowe WL Jr, Florkiewicz RZ, Yorek MA, Spanheimer RG, Albrecht BN.

    Metabolism. 1995 Aug;44(8):1038.PMID: 7637645 [PubMed - indexed for MEDLINE]Related articles

    6.

    Bax is increased in the retina of diabetic subjects and is associated with pericyte apoptosis in vivo and in vitro.

    Podestà F, Romeo G, Liu WH, Krajewski S, Reed JC, Gerhardinger C, Lorenzi M.

    Am J Pathol. 2000 Mar;156(3):1025-32.PMID: 10702418 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Differential insulin-like growth factor I receptor signaling and function in estrogen receptor (ER)-positive MCF-7 and ER-negative MDA-MB-231 breast cancer cells.

    Bartucci M, Morelli C, Mauro L, Andò S, Surmacz E.

    Cancer Res. 2001 Sep 15;61(18):6747-54.PMID: 11559546 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Up-regulation of integrin-linked kinase in the streptozotocin-induced diabetic rat retina.

    Li YJ, Hui YN, Yan F, Du ZJ.

    Graefes Arch Clin Exp Ophthalmol. 2007 Oct;245(10):1523-32. Epub 2007 Jul 26.PMID: 17653754 [PubMed - indexed for MEDLINE]Related articles

    9.

    Oral glutamine (AES-14) supplementation inhibits PI-3k/Akt signaling in experimental breast cancer.

    Todorova VK, Harms SA, Luo S, Kaufmann Y, Babb KB, Klimberg VS.

    JPEN J Parenter Enteral Nutr. 2003 Nov-Dec;27(6):404-10.PMID: 14621121 [PubMed - indexed for MEDLINE]Related articles

    10.

    Development of normal and injury-induced gene expression of aFGF, bFGF, CNTF, BDNF, GFAP and IGF-I in the rat retina.

    Cao W, Li F, Steinberg RH, Lavail MM.

    Exp Eye Res. 2001 May;72(5):591-604.PMID: 11311051 [PubMed - indexed for MEDLINE]Related articles

    11.

    Growth hormone (GH) and GH-releasing peptide-6 increase brain insulin-like growth factor-I expression and activate intracellular signaling pathways involved in neuroprotection.

    Frago LM, Pañeda C, Dickson SL, Hewson AK, Argente J, Chowen JA.

    Endocrinology. 2002 Oct;143(10):4113-22.PMID: 12239123 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    The insulin-like growth factor-I (IGF-I) receptor kinase inhibitor NVP-ADW742, in combination with STI571, delineates a spectrum of dependence of small cell lung cancer on IGF-I and stem cell factor signaling.

    Warshamana-Greene GS, Litz J, Buchdunger E, Hofmann F, García-Echeverría C, Krystal GW.

    Mol Cancer Ther. 2004 May;3(5):527-35.PMID: 15141010 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Saw palmetto extract suppresses insulin-like growth factor-I signaling and induces stress-activated protein kinase/c-Jun N-terminal kinase phosphorylation in human prostate epithelial cells.

    Wadsworth TL, Carroll JM, Mallinson RA, Roberts CT Jr, Roselli CE.

    Endocrinology. 2004 Jul;145(7):3205-14. Epub 2004 Mar 19.PMID: 15033918 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    The luteinizing hormone-releasing hormone inhibits the anti-apoptotic activity of insulin-like growth factor-1 in pituitary alphaT3 cells by protein kinase Calpha-mediated negative regulation of Akt.

    Rose A, Froment P, Perrot V, Quon MJ, LeRoith D, Dupont J.

    J Biol Chem. 2004 Dec 10;279(50):52500-16. Epub 2004 Sep 24.PMID: 15448167 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Dual effects of IGFBP-3 on endothelial cell apoptosis and survival: involvement of the sphingolipid signaling pathways.

    Granata R, Trovato L, Garbarino G, Taliano M, Ponti R, Sala G, Ghidoni R, Ghigo E.

    FASEB J. 2004 Sep;18(12):1456-8. Epub 2004 Jul 9.PMID: 15247143 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Akt is activated via insulin/IGF-1 receptor in rat retina with episcleral vein cauterization.

    Kanamori A, Nakamura M, Nakanishi Y, Nagai A, Mukuno H, Yamada Y, Negi A.

    Brain Res. 2004 Oct 1;1022(1-2):195-204.PMID: 15353229 [PubMed - indexed for MEDLINE]Related articles

    17.

    Diabetes reduces basal retinal insulin receptor signaling: reversal with systemic and local insulin.

    Reiter CE, Wu X, Sandirasegarane L, Nakamura M, Gilbert KA, Singh RS, Fort PE, Antonetti DA, Gardner TW.

    Diabetes. 2006 Apr;55(4):1148-56.PMID: 16567541 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Phosphatidylinositol 3-kinase (PI-3K)/Akt but not PI-3K/p70 S6 kinase signaling mediates IGF-1-promoted lens epithelial cell survival.

    Chandrasekher G, Sailaja D.

    Invest Ophthalmol Vis Sci. 2004 Oct;45(10):3577-88.PMID: 15452065 [PubMed - indexed for MEDLINE]Related articlesFree article

    19.

    Activation of nuclear factor-kappaB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes.

    Romeo G, Liu WH, Asnaghi V, Kern TS, Lorenzi M.

    Diabetes. 2002 Jul;51(7):2241-8.PMID: 12086956 [PubMed - indexed for MEDLINE]Related articlesFree article

    20.

    Specific retinal diacylglycerol and protein kinase C beta isoform modulation mimics abnormal retinal hemodynamics in diabetic rats.

    Bursell SE, Takagi C, Clermont AC, Takagi H, Mori F, Ishii H, King GL.

    Invest Ophthalmol Vis Sci. 1997 Dec;38(13):2711-20.PMID: 9418723 [PubMed - indexed for MEDLINE]Related articlesFree article

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