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Protease inhibitors do not interfere with prohormone processing.
Danoff A, Ling WL.
Ann Intern Med. 2000 Feb 15;132(4):330. No abstract available. PMID: 10681299 [PubMed - indexed for MEDLINE]Related articlesFree article
Synthetic peptides derived from the prosegments of proprotein convertase 1/3 and furin are potent inhibitors of both enzymes.
Basak A, Lazure C.
Biochem J. 2003 Jul 1;373(Pt 1):231-9.PMID: 12662153 [PubMed - indexed for MEDLINE]Related articlesFree article
The cystatin-related epididymal spermatogenic protein inhibits the serine protease prohormone convertase 2.
Cornwall GA, Cameron A, Lindberg I, Hardy DM, Cormier N, Hsia N.
Endocrinology. 2003 Mar;144(3):901-8.PMID: 12586766 [PubMed - indexed for MEDLINE]Related articlesFree article
Prohormone processing and Type 2 diabetes.
Jackson RS.
Diabet Med. 2001 Sep;18(9):773-4. No abstract available. PMID: 11606182 [PubMed - indexed for MEDLINE]Related articles
Protease inhibitors and prohormone processing.
Stricker RB, Goldberg B.
Ann Intern Med. 2000 Sep 19;133(6):482-3. No abstract available. PMID: 10975973 [PubMed - indexed for MEDLINE]Related articlesFree article
Defective prodynorphin processing in mice lacking prohormone convertase PC2.
Berman Y, Mzhavia N, Polonskaia A, Furuta M, Steiner DF, Pintar JE, Devi LA.
J Neurochem. 2000 Oct;75(4):1763-70.PMID: 10987860 [PubMed - indexed for MEDLINE]Related articles
Processing of synthetic pro-islet amyloid polypeptide (proIAPP) 'amylin' by recombinant prohormone convertase enzymes, PC2 and PC3, in vitro.
Higham CE, Hull RL, Lawrie L, Shennan KI, Morris JF, Birch NP, Docherty K, Clark A.
Eur J Biochem. 2000 Aug;267(16):4998-5004.PMID: 10931181 [PubMed - indexed for MEDLINE]Related articlesFree article
Tissue distribution and processing of proSAAS by proprotein convertases.
Sayah M, Fortenberry Y, Cameron A, Lindberg I.
J Neurochem. 2001 Mar;76(6):1833-41.PMID: 11259501 [PubMed - indexed for MEDLINE]Related articles
Processing of beta-secretase by furin and other members of the proprotein convertase family.
Creemers JW, Ines Dominguez D, Plets E, Serneels L, Taylor NA, Multhaup G, Craessaerts K, Annaert W, De Strooper B.
J Biol Chem. 2001 Feb 9;276(6):4211-7. Epub 2000 Nov 8.PMID: 11071887 [PubMed - indexed for MEDLINE]Related articlesFree article
Development of selectivity of alpha1-antitrypsin variant by mutagenesis in its reactive site loop against proprotein convertase. A crucial role of the P4 arginine in PACE4 inhibition.
Tsuji A, Ikoma T, Hashimoto E, Matsuda Y.
Protein Eng. 2002 Feb;15(2):123-30.PMID: 11917148 [PubMed - indexed for MEDLINE]Related articlesFree article
Short polybasic peptide sequences are potent inhibitors of PC5/6 and PC7: Use of positional scanning-synthetic peptide combinatorial libraries as a tool for the optimization of inhibitory sequences.
Fugere M, Appel J, Houghten RA, Lindberg I, Day R.
Mol Pharmacol. 2007 Jan;71(1):323-32. Epub 2006 Sep 29.PMID: 17012622 [PubMed - indexed for MEDLINE]Related articlesFree article
Processing of alpha4 integrin by the proprotein convertases: histidine at position P6 regulates cleavage.
Bergeron E, Basak A, Decroly E, Seidah NG.
Biochem J. 2003 Jul 15;373(Pt 2):475-84.PMID: 12691605 [PubMed - indexed for MEDLINE]Related articlesFree article
Proprotein convertases regulate activity of prostate epithelial cell differentiation markers and are modulated in human prostate cancer cells.
Uchida K, Chaudhary LR, Sugimura Y, Adkisson HD, Hruska KA.
J Cell Biochem. 2003 Feb 1;88(2):394-9.PMID: 12520542 [PubMed - indexed for MEDLINE]Related articles
Optimization of protease-inhibitor interactions by randomizing adventitious contacts.
Komiyama T, VanderLugt B, Fugère M, Day R, Kaufman RJ, Fuller RS.
Proc Natl Acad Sci U S A. 2003 Jul 8;100(14):8205-10. Epub 2003 Jun 27.PMID: 12832612 [PubMed - indexed for MEDLINE]Related articlesFree article
Proprotein convertases are important mediators of the adipocyte differentiation of mouse 3T3-L1 cells.
Croissandeau G, Basak A, Seidah NG, Chrétien M, Mbikay M.
J Cell Sci. 2002 Mar 15;115(Pt 6):1203-11.PMID: 11884519 [PubMed - indexed for MEDLINE]Related articlesFree article
Protease inhibitors and cardiovascular outcomes in patients with HIV-1.
Holmberg SD, Moorman AC, Williamson JM, Tong TC, Ward DJ, Wood KC, Greenberg AE, Janssen RS; HIV Outpatient Study (HOPS) investigators.
Lancet. 2002 Nov 30;360(9347):1747-8.PMID: 12480430 [PubMed - indexed for MEDLINE]Related articles
Knock-out mouse models of proprotein convertases: unique functions or redundancy?
Creemers JW, Khatib AM.
Front Biosci. 2008 May 1;13:4960-71. Review.PMID: 18508561 [PubMed - indexed for MEDLINE]Related articles
Mechanisms of alpha1-antitrypsin inhibition of cellular serine proteases and HIV-1 protease that are essential for HIV-1 morphogenesis.
Cordelier P, Strayer DS.
Biochim Biophys Acta. 2003 Jul 30;1638(3):197-207.PMID: 12878320 [PubMed - indexed for MEDLINE]Related articles
Processing of acidic proline-rich proprotein by human salivary gland convertase.
Cai K, Bennick A.
Arch Oral Biol. 2004 Nov;49(11):871-9.PMID: 15353242 [PubMed - indexed for MEDLINE]Related articles
[Pharma-clinics how I treat ... an HIV infection. IV. Protease inhibitors]
Léonard P, Nkoghe D, Moutschen M, Demonty J.
Rev Med Liege. 2001 Nov;56(11):739-44. French. PMID: 11789385 [PubMed - indexed for MEDLINE]Related articles
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