PubMed

Neonatal beta-cell apoptosis: a trigger for autoimmune diabetes?

Trudeau JD, Dutz JP, Arany E, Hill DJ, Fieldus WE, Finegood DT.

Diabetes. 2000 Jan;49(1):1-7. Review.PMID: 10615942 [PubMed - indexed for MEDLINE]Related articlesFree article

Clearance of apoptotic beta-cells is reduced in neonatal autoimmune diabetes-prone rats.

O'Brien BA, Fieldus WE, Field CJ, Finegood DT.

Cell Death Differ. 2002 Apr;9(4):457-64.PMID: 11965499 [PubMed - indexed for MEDLINE]Related articlesFree article

Cellular and molecular pathogenic mechanisms of insulin-dependent diabetes mellitus.

Yoon JW, Jun HS.

Ann N Y Acad Sci. 2001 Apr;928:200-11. Review.PMID: 11795511 [PubMed - indexed for MEDLINE]Related articles

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

Scaglia L, Cahill CJ, Finegood DT, Bonner-Weir S.

Endocrinology. 1997 Apr;138(4):1736-41.PMID: 9075738 [PubMed - indexed for MEDLINE]Related articlesFree article

Surface and intracellular Fas expression associated with cytokine-induced apoptosis in rodent islet and insulinoma cells.

Augstein P, Wachlin G, Berg S, Bahr J, Salzsieder C, Hehmke B, Heinke P, Salzsieder E.

J Mol Endocrinol. 2003 Apr;30(2):163-71.PMID: 12683940 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased beta-cell apoptosis prevents adaptive increase in beta-cell mass in mouse model of type 2 diabetes: evidence for role of islet amyloid formation rather than direct action of amyloid.

Butler AE, Janson J, Soeller WC, Butler PC.

Diabetes. 2003 Sep;52(9):2304-14.PMID: 12941770 [PubMed - indexed for MEDLINE]Related articlesFree article

Transplacental exposure to the vacuolar-ATPase inhibitor bafilomycin disrupts survival signaling in beta cells and delays neonatal remodeling of the endocrine pancreas.

Hettiarachchi KD, Zimmet PZ, Danial NN, Myers MA.

Exp Toxicol Pathol. 2008 Aug;60(4-5):295-306. Epub 2008 May 16.PMID: 18486461 [PubMed - indexed for MEDLINE]Related articles

Transplacental exposure to bafilomycin disrupts pancreatic islet organogenesis and accelerates diabetes onset in NOD mice.

Hettiarachchi KD, Zimmet PZ, Myers MA.

J Autoimmun. 2004 Jun;22(4):287-96.PMID: 15120752 [PubMed - indexed for MEDLINE]Related articles

Nicotinamide prevents the development of diabetes in the cyclophosphamide-induced NOD mouse model by reducing beta-cell apoptosis.

O'Brien BA, Harmon BV, Cameron DP, Allan DJ.

J Pathol. 2000 May;191(1):86-92.PMID: 10767724 [PubMed - indexed for MEDLINE]Related articles

Beta-cell deficit due to increased apoptosis in the human islet amyloid polypeptide transgenic (HIP) rat recapitulates the metabolic defects present in type 2 diabetes.

Matveyenko AV, Butler PC.

Diabetes. 2006 Jul;55(7):2106-14.PMID: 16804082 [PubMed - indexed for MEDLINE]Related articlesFree article

Caspase-3-dependent beta-cell apoptosis in the initiation of autoimmune diabetes mellitus.

Liadis N, Murakami K, Eweida M, Elford AR, Sheu L, Gaisano HY, Hakem R, Ohashi PS, Woo M.

Mol Cell Biol. 2005 May;25(9):3620-9.PMID: 15831467 [PubMed - indexed for MEDLINE]Related articlesFree article

Diabetes due to a progressive defect in beta-cell mass in rats transgenic for human islet amyloid polypeptide (HIP Rat): a new model for type 2 diabetes.

Butler AE, Jang J, Gurlo T, Carty MD, Soeller WC, Butler PC.

Diabetes. 2004 Jun;53(6):1509-16.PMID: 15161755 [PubMed - indexed for MEDLINE]Related articlesFree article

IFN-gamma/TNF-alpha synergism as the final effector in autoimmune diabetes: a key role for STAT1/IFN regulatory factor-1 pathway in pancreatic beta cell death.

Suk K, Kim S, Kim YH, Kim KA, Chang I, Yagita H, Shong M, Lee MS.

J Immunol. 2001 Apr 1;166(7):4481-9.PMID: 11254704 [PubMed - indexed for MEDLINE]Related articlesFree article

Replication increases beta-cell vulnerability to human islet amyloid polypeptide-induced apoptosis.

Ritzel RA, Butler PC.

Diabetes. 2003 Jul;52(7):1701-8.PMID: 12829636 [PubMed - indexed for MEDLINE]Related articlesFree article

A choice of death--the signal-transduction of immune-mediated beta-cell apoptosis.

Eizirik DL, Mandrup-Poulsen T.

Diabetologia. 2001 Dec;44(12):2115-33. Review. Erratum in: Diabetologia. 2002 Jun;45(6):936.. PMID: 11793013 [PubMed - indexed for MEDLINE]Related articles

B cells are crucial for determinant spreading of T cell autoimmunity among beta cell antigens in diabetes-prone nonobese diabetic mice.

Tian J, Zekzer D, Lu Y, Dang H, Kaufman DL.

J Immunol. 2006 Feb 15;176(4):2654-61.PMID: 16456028 [PubMed - indexed for MEDLINE]Related articlesFree article

Increased and persistent circulating insulin-like growth factor II in neonatal transgenic mice suppresses developmental apoptosis in the pancreatic islets.

Hill DJ, Strutt B, Arany E, Zaina S, Coukell S, Graham CF.

Endocrinology. 2000 Mar;141(3):1151-7.PMID: 10698192 [PubMed - indexed for MEDLINE]Related articlesFree article

Immunohistochemical study of caspase-3-expressing cells within the pancreas of non-obese diabetic mice during cyclophosphamide-accelerated diabetes.

Reddy S, Bradley J, Ginn S, Pathipati P, Ross JM.

Histochem Cell Biol. 2003 Jun;119(6):451-61. Epub 2003 Jun 11.PMID: 12802593 [PubMed - indexed for MEDLINE]Related articles

Control of type 1 autoimmune diabetes by naturally occurring CD4+CD25+ regulatory T lymphocytes in neonatal NOD mice.

Piccirillo CA, Tritt M, Sgouroudis E, Albanese A, Pyzik M, Hay V.

Ann N Y Acad Sci. 2005 Jun;1051:72-87. Review.PMID: 16126946 [PubMed - indexed for MEDLINE]Related articles

Beneficial autoimmunity in Type 1 diabetes mellitus.

Hauben E, Roncarolo MG, Nevo U, Schwartz M.

Trends Immunol. 2005 May;26(5):248-53.PMID: 15866237 [PubMed - indexed for MEDLINE]Related articles