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    Results: 1 to 20 of 416

    1.

    Beneficial effects of antioxidants in diabetes: possible protection of pancreatic beta-cells against glucose toxicity.

    Kaneto H, Kajimoto Y, Miyagawa J, Matsuoka T, Fujitani Y, Umayahara Y, Hanafusa T, Matsuzawa Y, Yamasaki Y, Hori M.

    Diabetes. 1999 Dec;48(12):2398-406.PMID: 10580429 [PubMed - indexed for MEDLINE]Related articlesFree article

    2.

    Role of oxidative stress in pancreatic beta-cell dysfunction.

    Kajimoto Y, Kaneto H.

    Ann N Y Acad Sci. 2004 Apr;1011:168-76.PMID: 15126294 [PubMed - indexed for MEDLINE]Related articles

    3.

    Probucol preserves pancreatic beta-cell function through reduction of oxidative stress in type 2 diabetes.

    Gorogawa S, Kajimoto Y, Umayahara Y, Kaneto H, Watada H, Kuroda A, Kawamori D, Yasuda T, Matsuhisa M, Yamasaki Y, Hori M.

    Diabetes Res Clin Pract. 2002 Jul;57(1):1-10.PMID: 12007724 [PubMed - indexed for MEDLINE]Related articles

    4.

    Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice.

    Uchiyama K, Naito Y, Hasegawa G, Nakamura N, Takahashi J, Yoshikawa T.

    Redox Rep. 2002;7(5):290-3.PMID: 12688512 [PubMed - indexed for MEDLINE]Related articles

    5.

    Pioglitazone improves insulin secretory capacity and prevents the loss of beta-cell mass in obese diabetic db/db mice: Possible protection of beta cells from oxidative stress.

    Ishida H, Takizawa M, Ozawa S, Nakamichi Y, Yamaguchi S, Katsuta H, Tanaka T, Maruyama M, Katahira H, Yoshimoto K, Itagaki E, Nagamatsu S.

    Metabolism. 2004 Apr;53(4):488-94.PMID: 15045697 [PubMed - indexed for MEDLINE]Related articles

    6.

    Oxidative stress and the JNK pathway as a potential therapeutic target for diabetes.

    Kaneto H, Kawamori D, Nakatani Y, Gorogawa S, Matsuoka TA.

    Drug News Perspect. 2004 Sep;17(7):447-53. Review.PMID: 15514704 [PubMed - indexed for MEDLINE]Related articles

    7.

    Prevention of glucose toxicity in HIT-T15 cells and Zucker diabetic fatty rats by antioxidants.

    Tanaka Y, Gleason CE, Tran PO, Harmon JS, Robertson RP.

    Proc Natl Acad Sci U S A. 1999 Sep 14;96(19):10857-62.PMID: 10485916 [PubMed - indexed for MEDLINE]Related articlesFree article

    8.

    Amelioration of the beta-cell dysfunction in diabetic APA hamsters by antioxidants and AGE inhibitor treatments.

    Takatori A, Ishii Y, Itagaki S, Kyuwa S, Yoshikawa Y.

    Diabetes Metab Res Rev. 2004 May-Jun;20(3):211-8.PMID: 15133752 [PubMed - indexed for MEDLINE]Related articles

    9.

    Estrogenic restoration of functional pancreatic islet cytoarchitecture in diabetes (db/db) mutant C57BL/KsJ mice: relationship to estradiol localization, systemic glycemia, and persistent hyperinsulinemia.

    Garris DR, Garris BL.

    Cell Tissue Res. 2005 Feb;319(2):231-42. Epub 2004 Nov 20.PMID: 15654653 [PubMed - indexed for MEDLINE]Related articles

    10.

    Reduction of oxidative stress by a new low-molecular-weight antioxidant improves metabolic alterations in a nonobese mouse diabetes model.

    Novelli M, D'Aleo V, Lupi R, Paolini M, Soleti A, Marchetti P, Masiello P.

    Pancreas. 2007 Nov;35(4):e10-7.PMID: 18090226 [PubMed - indexed for MEDLINE]Related articles

    11.

    Glucose toxicity in beta-cells: type 2 diabetes, good radicals gone bad, and the glutathione connection.

    Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H.

    Diabetes. 2003 Mar;52(3):581-7. Review.PMID: 12606496 [PubMed - indexed for MEDLINE]Related articlesFree article

    12.

    [Effects of angiotensin II type 1 receptor blocker on islet of diabetic db/db mice]

    Shao JQ, Iwashita N, Du H, Wang YY, Zhao M, Wang J, Watada H, Kawamori R.

    Zhonghua Nei Ke Za Zhi. 2007 Apr;46(4):306-10. Chinese. PMID: 17637271 [PubMed - indexed for MEDLINE]Related articles

    13.

    Structural and functional analysis of pancreatic islets preserved by pioglitazone in db/db mice.

    Kawasaki F, Matsuda M, Kanda Y, Inoue H, Kaku K.

    Am J Physiol Endocrinol Metab. 2005 Mar;288(3):E510-8. Epub 2004 Nov 2.PMID: 15522998 [PubMed - indexed for MEDLINE]Related articlesFree article

    14.

    Pioglitazone preserves pancreatic islet structure and insulin secretory function in three murine models of type 2 diabetes.

    Diani AR, Sawada G, Wyse B, Murray FT, Khan M.

    Am J Physiol Endocrinol Metab. 2004 Jan;286(1):E116-22. Epub 2003 Oct 7.PMID: 14532171 [PubMed - indexed for MEDLINE]Related articlesFree article

    15.

    Free fatty acid-induced reduction in glucose-stimulated insulin secretion: evidence for a role of oxidative stress in vitro and in vivo.

    Oprescu AI, Bikopoulos G, Naassan A, Allister EM, Tang C, Park E, Uchino H, Lewis GF, Fantus IG, Rozakis-Adcock M, Wheeler MB, Giacca A.

    Diabetes. 2007 Dec;56(12):2927-37. Epub 2007 Aug 23.PMID: 17717282 [PubMed - indexed for MEDLINE]Related articlesFree article

    16.

    Beneficial effects of candesartan, an angiotensin II type 1 receptor blocker, on beta-cell function and morphology in db/db mice.

    Shao J, Iwashita N, Ikeda F, Ogihara T, Uchida T, Shimizu T, Uchino H, Hirose T, Kawamori R, Watada H.

    Biochem Biophys Res Commun. 2006 Jun 16;344(4):1224-33. Epub 2006 Apr 21.PMID: 16650382 [PubMed - indexed for MEDLINE]Related articles

    17.

    Combination of the dipeptidyl peptidase IV inhibitor LAF237 [(S)-1-[(3-hydroxy-1-adamantyl)ammo]acetyl-2-cyanopyrrolidine] with the angiotensin II type 1 receptor antagonist valsartan [N-(1-oxopentyl)-N-[[2'-(1H-tetrazol-5-yl)-[1,1'-biphenyl]-4-yl]methyl]-L-valine] enhances pancreatic islet morphology and function in a mouse model of type 2 diabetes.

    Cheng Q, Law PK, de Gasparo M, Leung PS.

    J Pharmacol Exp Ther. 2008 Dec;327(3):683-91. Epub 2008 Sep 11.PMID: 18787107 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    Pancreatic beta cell senescence contributes to the pathogenesis of type 2 diabetes in high-fat diet-induced diabetic mice.

    Sone H, Kagawa Y.

    Diabetologia. 2005 Jan;48(1):58-67. Epub 2004 Dec 29.PMID: 15624098 [PubMed - indexed for MEDLINE]Related articles

    19.

    Glucagon-like peptide-1 treatment delays the onset of diabetes in 8 week-old db/db mice.

    Wang Q, Brubaker PL.

    Diabetologia. 2002 Sep;45(9):1263-73. Epub 2002 Apr 26.PMID: 12242459 [PubMed - indexed for MEDLINE]Related articles

    20.

    Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes.

    Robertson R, Zhou H, Zhang T, Harmon JS.

    Cell Biochem Biophys. 2007;48(2-3):139-46.PMID: 17709883 [PubMed - indexed for MEDLINE]Related articles

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