PubMed

Oral administration of cholera toxin B-insulin conjugates protects NOD mice from autoimmune diabetes by inducing CD4+ regulatory T-cells.

Ploix C, Bergerot I, Durand A, Czerkinsky C, Holmgren J, Thivolet C.

Diabetes. 1999 Nov;48(11):2150-6.PMID: 10535448 [PubMed - indexed for MEDLINE]Related articlesFree article

Nasal administration of CTB-insulin induces active tolerance against autoimmune diabetes in non-obese diabetic (NOD) mice.

Aspord C, Thivolet C.

Clin Exp Immunol. 2002 Nov;130(2):204-11.PMID: 12390307 [PubMed - indexed for MEDLINE]Related articlesFree article

Protection against autoimmune diabetes with oral insulin is associated with the presence of IL-4 type 2 T-cells in the pancreas and pancreatic lymph nodes.

Ploix C, Bergerot I, Fabien N, Perche S, Moulin V, Thivolet C.

Diabetes. 1998 Jan;47(1):39-44.PMID: 9421372 [PubMed - indexed for MEDLINE]Related articles

alpha4 integrins and L-selectin differently orchestrate T-cell activity during diabetes prevention following oral administration of CTB-insulin.

Aspord C, Czerkinsky C, Durand A, Stefanutti A, Thivolet C.

J Autoimmun. 2002 Dec;19(4):223-32.PMID: 12473243 [PubMed - indexed for MEDLINE]Related articles

A cholera toxoid-insulin conjugate as an oral vaccine against spontaneous autoimmune diabetes.

Bergerot I, Ploix C, Petersen J, Moulin V, Rask C, Fabien N, Lindblad M, Mayer A, Czerkinsky C, Holmgren J, Thivolet C.

Proc Natl Acad Sci U S A. 1997 Apr 29;94(9):4610-4.PMID: 9114038 [PubMed - indexed for MEDLINE]Related articlesFree article

Enhanced immunological tolerance against allograft rejection by oral administration of allogeneic antigen linked to cholera toxin B subunit.

Sun JB, Li BL, Czerkinsky C, Holmgren J.

Clin Immunol. 2000 Nov;97(2):130-9.PMID: 11027453 [PubMed - indexed for MEDLINE]Related articles

The CXCR4/CXCL12 (SDF-1) signalling pathway protects non-obese diabetic mouse from autoimmune diabetes.

Aboumrad E, Madec AM, Thivolet C.

Clin Exp Immunol. 2007 Jun;148(3):432-9. Epub 2007 Mar 21.PMID: 17374136 [PubMed - indexed for MEDLINE]Related articlesFree article

Both CD4+ and CD8+ T-cells in syngeneic islet grafts in NOD mice produce interferon-gamma during beta-cell destruction.

Suarez-Pinzon W, Rajotte RV, Mosmann TR, Rabinovitch A.

Diabetes. 1996 Oct;45(10):1350-7.PMID: 8826970 [PubMed - indexed for MEDLINE]Related articles

Early Th1 response in unprimed nonobese diabetic mice to the tyrosine phosphatase-like insulinoma-associated protein 2, an autoantigen in type 1 diabetes.

Trembleau S, Penna G, Gregori S, Magistrelli G, Isacchi A, Adorini L.

J Immunol. 2000 Dec 15;165(12):6748-55.PMID: 11120794 [PubMed - indexed for MEDLINE]Related articlesFree article

CD4+CD25+ regulatory T cells generated in response to insulin B:9-23 peptide prevent adoptive transfer of diabetes by diabetogenic T cells.

Mukherjee R, Chaturvedi P, Qin HY, Singh B.

J Autoimmun. 2003 Nov;21(3):221-37.PMID: 14599847 [PubMed - indexed for MEDLINE]Related articles

Sublingual tolerance induction with antigen conjugated to cholera toxin B subunit induces Foxp3+CD25+CD4+ regulatory T cells and suppresses delayed-type hypersensitivity reactions.

Sun JB, Cuburu N, Blomquist M, Li BL, Czerkinsky C, Holmgren J.

Scand J Immunol. 2006 Sep;64(3):251-9.PMID: 16918694 [PubMed - indexed for MEDLINE]Related articles

Insulin B-chain reactive CD4+ regulatory T-cells induced by oral insulin treatment protect from type 1 diabetes by blocking the cytokine secretion and pancreatic infiltration of diabetogenic effector T-cells.

Bergerot I, Arreaza GA, Cameron MJ, Burdick MD, Strieter RM, Chensue SW, Chakrabarti S, Delovitch TL.

Diabetes. 1999 Sep;48(9):1720-9.PMID: 10480600 [PubMed - indexed for MEDLINE]Related articlesFree article

Suppression of insulitis in non-obese diabetic (NOD) mice by oral insulin administration is associated with selective expression of interleukin-4 and -10, transforming growth factor-beta, and prostaglandin-E.

Hancock WW, Polanski M, Zhang J, Blogg N, Weiner HL.

Am J Pathol. 1995 Nov;147(5):1193-9.PMID: 7485382 [PubMed - indexed for MEDLINE]Related articlesFree article

The cholera toxin B subunit is a mucosal adjuvant for oral tolerance induction in type 1 diabetes.

Bregenholt S, Wang M, Wolfe T, Hughes A, Baerentzen L, Dyrberg T, von Herrath MG, Petersen JS.

Scand J Immunol. 2003 May;57(5):432-8.PMID: 12753499 [PubMed - indexed for MEDLINE]Related articles

Regional oral tolerance in transgenic 2C mice.

Margenthaler JA, Flye MW.

Surgery. 2005 Aug;138(2):141-9.PMID: 16153420 [PubMed - indexed for MEDLINE]Related articles

Upregulating CD4+CD25+FOXP3+ regulatory T cells in pancreatic lymph nodes in diabetic NOD mice by adjuvant immunotherapy.

Tian B, Hao J, Zhang Y, Tian L, Yi H, O'Brien TD, Sutherland DE, Hering BJ, Guo Z.

Transplantation. 2009 Jan 27;87(2):198-206.PMID: 19155973 [PubMed - indexed for MEDLINE]Related articles

Prevention of autoimmune diabetes in NOD mice by troglitazone is associated with modulation of ICAM-1 expression on pancreatic islet cells and IFN-gamma expression in splenic T cells.

Augstein P, Dunger A, Heinke P, Wachlin G, Berg S, Hehmke B, Salzsieder E.

Biochem Biophys Res Commun. 2003 May 2;304(2):378-84.PMID: 12711326 [PubMed - indexed for MEDLINE]Related articles

Oral tolerance induction by mucosal administration of cholera toxin B-coupled antigen involves T-cell proliferation in vivo and is not affected by depletion of CD25+ T cells.

George Chandy A, Hultkrantz S, Raghavan S, Czerkinsky C, Lebens M, Telemo E, Holmgren J.

Immunology. 2006 Jul;118(3):311-20.PMID: 16827892 [PubMed - indexed for MEDLINE]Related articlesFree article

1alpha,25-dihydroxyvitamin D3 induces an autoantigen-specific T-helper 1/T-helper 2 immune shift in NOD mice immunized with GAD65 (p524-543).

Overbergh L, Decallonne B, Waer M, Rutgeerts O, Valckx D, Casteels KM, Laureys J, Bouillon R, Mathieu C.

Diabetes. 2000 Aug;49(8):1301-7.PMID: 10923629 [PubMed - indexed for MEDLINE]Related articlesFree article

IL-12 administration accelerates autoimmune diabetes in both wild-type and IFN-gamma-deficient nonobese diabetic mice, revealing pathogenic and protective effects of IL-12-induced IFN-gamma.

Trembleau S, Penna G, Gregori S, Giarratana N, Adorini L.

J Immunol. 2003 Jun 1;170(11):5491-501.PMID: 12759426 [PubMed - indexed for MEDLINE]Related articlesFree article