PubMed

5' AMP-activated protein kinase activation causes GLUT4 translocation in skeletal muscle.

Kurth-Kraczek EJ, Hirshman MF, Goodyear LJ, Winder WW.

Diabetes. 1999 Aug;48(8):1667-71.PMID: 10426389 [PubMed - indexed for MEDLINE]Related articlesFree article

AICA riboside increases AMP-activated protein kinase, fatty acid oxidation, and glucose uptake in rat muscle.

Merrill GF, Kurth EJ, Hardie DG, Winder WW.

Am J Physiol. 1997 Dec;273(6 Pt 1):E1107-12.PMID: 9435525 [PubMed - indexed for MEDLINE]Related articlesFree article

Glycogen-dependent effects of 5-aminoimidazole-4-carboxamide (AICA)-riboside on AMP-activated protein kinase and glycogen synthase activities in rat skeletal muscle.

Wojtaszewski JF, Jørgensen SB, Hellsten Y, Hardie DG, Richter EA.

Diabetes. 2002 Feb;51(2):284-92.PMID: 11812734 [PubMed - indexed for MEDLINE]Related articlesFree article

The AMP-activated protein kinase activator AICAR does not induce GLUT4 translocation to transverse tubules but stimulates glucose uptake and p38 mitogen-activated protein kinases alpha and beta in skeletal muscle.

Lemieux K, Konrad D, Klip A, Marette A.

FASEB J. 2003 Sep;17(12):1658-65.PMID: 12958172 [PubMed - indexed for MEDLINE]Related articlesFree article

Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells.

Fryer LG, Foufelle F, Barnes K, Baldwin SA, Woods A, Carling D.

Biochem J. 2002 Apr 1;363(Pt 1):167-74.PMID: 11903059 [PubMed - indexed for MEDLINE]Related articlesFree article

Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes.

Yamaguchi S, Katahira H, Ozawa S, Nakamichi Y, Tanaka T, Shimoyama T, Takahashi K, Yoshimoto K, Imaizumi MO, Nagamatsu S, Ishida H.

Am J Physiol Endocrinol Metab. 2005 Oct;289(4):E643-9. Epub 2005 May 31.PMID: 15928020 [PubMed - indexed for MEDLINE]Related articlesFree article

AMP-activated protein kinase: possible target for treatment of type 2 diabetes.

Winder WW.

Diabetes Technol Ther. 2000 Autumn;2(3):441-8. Review.PMID: 11467346 [PubMed - indexed for MEDLINE]Related articles

Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle.

Li J, Hu X, Selvakumar P, Russell RR 3rd, Cushman SW, Holman GD, Young LH.

Am J Physiol Endocrinol Metab. 2004 Nov;287(5):E834-41. Epub 2004 Jul 20.PMID: 15265762 [PubMed - indexed for MEDLINE]Related articlesFree article

alpha2 Isoform-specific activation of 5'adenosine monophosphate-activated protein kinase by 5-aminoimidazole-4-carboxamide-1-beta-d-ribonucleoside at a physiological level activates glucose transport and increases glucose transporter 4 in mouse skeletal muscle.

Nakano M, Hamada T, Hayashi T, Yonemitsu S, Miyamoto L, Toyoda T, Tanaka S, Masuzaki H, Ebihara K, Ogawa Y, Hosoda K, Inoue G, Yoshimasa Y, Otaka A, Fushiki T, Nakao K.

Metabolism. 2006 Mar;55(3):300-8.PMID: 16483872 [PubMed - indexed for MEDLINE]Related articles

Relationship between 5-aminoimidazole-4-carboxamide-ribotide and AMP-activated protein kinase activity in the perfused mouse heart.

Zhang L, Frederich M, He H, Balschi JA.

Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1235-43. Epub 2005 Oct 28.PMID: 16258030 [PubMed - indexed for MEDLINE]Related articlesFree article

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR.

Russell RR 3rd, Bergeron R, Shulman GI, Young LH.

Am J Physiol. 1999 Aug;277(2 Pt 2):H643-9.PMID: 10444490 [PubMed - indexed for MEDLINE]Related articlesFree article

Insulin stimulation of glucose uptake fails to decrease palmitate oxidation in muscle if AMPK is activated.

Winder WW, Holmes BF.

J Appl Physiol. 2000 Dec;89(6):2430-7.PMID: 11090599 [PubMed - indexed for MEDLINE]Related articlesFree article

Evidence for 5' AMP-activated protein kinase mediation of the effect of muscle contraction on glucose transport.

Hayashi T, Hirshman MF, Kurth EJ, Winder WW, Goodyear LJ.

Diabetes. 1998 Aug;47(8):1369-73.PMID: 9703344 [PubMed - indexed for MEDLINE]Related articlesFree article

Protein kinase inhibitors block the stimulation of the AMP-activated protein kinase by 5-amino-4-imidazolecarboxamide riboside.

Fryer LG, Parbu-Patel A, Carling D.

FEBS Lett. 2002 Nov 6;531(2):189-92.PMID: 12417310 [PubMed - indexed for MEDLINE]Related articles

Chronic treatment with 5-aminoimidazole-4-carboxamide-1-beta-D-ribofuranoside increases insulin-stimulated glucose uptake and GLUT4 translocation in rat skeletal muscles in a fiber type-specific manner.

Buhl ES, Jessen N, Schmitz O, Pedersen SB, Pedersen O, Holman GD, Lund S.

Diabetes. 2001 Jan;50(1):12-7.PMID: 11147776 [PubMed - indexed for MEDLINE]Related articlesFree article

Activation of glucose transport by AMP-activated protein kinase via stimulation of nitric oxide synthase.

Fryer LG, Hajduch E, Rencurel F, Salt IP, Hundal HS, Hardie DG, Carling D.

Diabetes. 2000 Dec;49(12):1978-85.PMID: 11117997 [PubMed - indexed for MEDLINE]Related articlesFree article

Effects of AICAR and exercise on insulin-stimulated glucose uptake, signaling, and GLUT-4 content in rat muscles.

Jessen N, Pold R, Buhl ES, Jensen LS, Schmitz O, Lund S.

J Appl Physiol. 2003 Apr;94(4):1373-9. Epub 2002 Dec 20.PMID: 12496137 [PubMed - indexed for MEDLINE]Related articlesFree article

AICA riboside both activates AMP-activated protein kinase and competes with adenosine for the nucleoside transporter in the CA1 region of the rat hippocampus.

Gadalla AE, Pearson T, Currie AJ, Dale N, Hawley SA, Sheehan M, Hirst W, Michel AD, Randall A, Hardie DG, Frenguelli BG.

J Neurochem. 2004 Mar;88(5):1272-82.PMID: 15009683 [PubMed - indexed for MEDLINE]Related articles

AMP-activated protein kinase-independent inhibition of hepatic mitochondrial oxidative phosphorylation by AICA riboside.

Guigas B, Taleux N, Foretz M, Detaille D, Andreelli F, Viollet B, Hue L.

Biochem J. 2007 Jun 15;404(3):499-507.PMID: 17324122 [PubMed - indexed for MEDLINE]Related articlesFree article

5-amino-imidazole carboxamide riboside increases glucose transport and cell-surface GLUT4 content in skeletal muscle from subjects with type 2 diabetes.

Koistinen HA, Galuska D, Chibalin AV, Yang J, Zierath JR, Holman GD, Wallberg-Henriksson H.

Diabetes. 2003 May;52(5):1066-72.PMID: 12716734 [PubMed - indexed for MEDLINE]Related articlesFree article