PubMed for id: 839

Year	Number of Results
1994	1
1995	1
1996	6
1997	4
1998	3
1999	10
2000	5
2001	10
2002	10
2003	1
2004	11
2005	5
2006	5
2007	5
2008	11
2009	14
2010	15
2011	11
2012	7
2013	7
2014	8
2015	1
2016	6
2017	5
2018	3
2019	4
2020	6
2021	4
2022	2
2023	6
2024	0

1

Dissection of pyroptosis-related prognostic signature and CASP6-mediated regulation in pancreatic adenocarcinoma: new sights to clinical decision-making.

Zhu J, Shi Y, Lan S, Wang J, Jiang F, Tang C, Cai Y, Pan Z, Jian H, Fang H, Zhang Y, Zhong F. Zhu J, et al. Apoptosis. 2023 Jun;28(5-6):769-782. doi: 10.1007/s10495-023-01823-7. Epub 2023 Mar 7. Apoptosis. 2023. PMID: 36882663 Free PMC article.

2

Caspase-6 is a key regulator of cross-talk signal way in PANoptosis in cancer.

Qi L, Wang L, Jin M, Jiang M, Li L, Li Y. Qi L, et al. Immunology. 2023 Jul;169(3):245-259. doi: 10.1111/imm.13633. Epub 2023 Mar 4. Immunology. 2023. PMID: 36814103 Review.

3

Rare CASP6N73T variant associated with hippocampal volume exhibits decreased proteolytic activity, synaptic transmission defect, and neurodegeneration.

Zhou L, Nho K, Haddad MG, Cherepacha N, Tubeleviciute-Aydin A, Tsai AP, Saykin AJ, Jesper Sjöström P, LeBlanc AC. Zhou L, et al. Sci Rep. 2021 Jun 16;11(1):12695. doi: 10.1038/s41598-021-91367-0. Sci Rep. 2021. PMID: 34135352 Free PMC article.

4

Identification of Allosteric Inhibitors against Active Caspase-6.

Tubeleviciute-Aydin A, Beautrait A, Lynham J, Sharma G, Gorelik A, Deny LJ, Soya N, Lukacs GL, Nagar B, Marinier A, LeBlanc AC. Tubeleviciute-Aydin A, et al. Sci Rep. 2019 Apr 2;9(1):5504. doi: 10.1038/s41598-019-41930-7. Sci Rep. 2019. PMID: 30940883 Free PMC article.

5

Tri-arginine exosite patch of caspase-6 recruits substrates for hydrolysis.

MacPherson DJ, Mills CL, Ondrechen MJ, Hardy JA. MacPherson DJ, et al. J Biol Chem. 2019 Jan 4;294(1):71-88. doi: 10.1074/jbc.RA118.005914. Epub 2018 Nov 12. J Biol Chem. 2019. PMID: 30420425 Free PMC article.

6

Rare human Caspase-6-R65W and Caspase-6-G66R variants identify a novel regulatory region of Caspase-6 activity.

Tubeleviciute-Aydin A, Zhou L, Sharma G, Soni IV, Savinov SN, Hardy JA, LeBlanc AC. Tubeleviciute-Aydin A, et al. Sci Rep. 2018 Mar 13;8(1):4428. doi: 10.1038/s41598-018-22283-z. Sci Rep. 2018. PMID: 29535332 Free PMC article.

7

Multiple proteolytic events in caspase-6 self-activation impact conformations of discrete structural regions.

Dagbay KB, Hardy JA. Dagbay KB, et al. Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E7977-E7986. doi: 10.1073/pnas.1704640114. Epub 2017 Sep 1. Proc Natl Acad Sci U S A. 2017. PMID: 28864531 Free PMC article.

8

Tumor-Associated Mutations in Caspase-6 Negatively Impact Catalytic Efficiency.

Dagbay KB, Hill ME, Barrett E, Hardy JA. Dagbay KB, et al. Biochemistry. 2017 Aug 29;56(34):4568-4577. doi: 10.1021/acs.biochem.7b00357. Epub 2017 Aug 16. Biochemistry. 2017. PMID: 28726391 Free PMC article.

9

Caspase-6 Undergoes a Distinct Helix-Strand Interconversion upon Substrate Binding.

Dagbay KB, Bolik-Coulon N, Savinov SN, Hardy JA. Dagbay KB, et al. J Biol Chem. 2017 Mar 24;292(12):4885-4897. doi: 10.1074/jbc.M116.773499. Epub 2017 Feb 2. J Biol Chem. 2017. PMID: 28154009 Free PMC article.

10

Increased Caspase-6 activity in the human anterior olfactory nuclei of the olfactory bulb is associated with cognitive impairment.

Foveau B, Albrecht S, Bennett DA, Correa JA, LeBlanc AC. Foveau B, et al. Acta Neuropathol Commun. 2016 Dec 8;4(1):127. doi: 10.1186/s40478-016-0400-x. Acta Neuropathol Commun. 2016. PMID: 27931265 Free PMC article.

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