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38311286,36729482,36345711,33635272,32176858,31609444,30418664,28848392,28277610,27416809,26213336,25890330,24651014,23567106,22998557,22452482,21912175,21680900,21295524,20079214,19050233,18226990,18214313,17890364,17035290,16973960,16621624,15149848,12244551,12244550,38157296,35792302,35349480,35263601,34252231,33378407,32065591,31913453,31273345,30580328,30529759,30075174,29162437,28139517,27407072,27129289,27036007,26507745,26249804,25767274,25499214,25283993,24429522,24391948,24098521,24012753,23371561,22504165,21712044,21328691,21156172,19667086,19389370,19325125,19265135,19208348,18688026,18591437,18157569,17366661,16875832,16647886,16163386,15550486,15486060,10906776,37021797,35939687,34758082,34428401,33127852,33046710,31469182,30168730,30010003,29126263,28863329,28027303,27659682,26286942,26228240,26191142,24530424,24478388,24191040,23863842,23833236,23530123,23489689,22887872,22753939,22028443,20628038,20154142,19935714,18365007,18292500,18184658,16867989,16378597,15939383,15634680,14988227,11841846,11427524,11259677,11181574,11067884,10679295,10556292,10473135,9716576,9207788,9207787,8955070,37756541,36376768,31704879,31673056,31345231,29199954,29141232,28699891,28537242,28045060,25535084,24398584,23630352,23267012,22390640,21220737,20940224,20602435,19524514,19147503,19026002,18383037,15060169,11861489,10837254,10329626,9858728,35064244,33268505,30991836,29217079,28566723,28051360,27869648,26465397,23526493,20388655,18848976,17947672,16736472,15882997,15788413,12175503,11713346,36044575,31071093,30930165,30065304,29627423,27939883,26884396,26235536,25257302,22147907,21472480,21156799,20870935,20720151,16410827,12244553,9108364,8923452,31076486,30226866,29093270,28561022,27271278,26276215,25778822,24711412,23467742,21959220,21472479,20038814,19598246,16908629,16495313,15226394,12846471,12835383,12010793,11960707,10551863,9463360,36347256,28952437,28838968,27633988,27354375,27050391,24647000,22652674,22156581,21490058,21238454,19914235,19011097,18515089,18245384,17626181,15161092,15064243,12242716,11528388,11344305,11044610,9272948,9207795,33113370,30929920,30758286,28779009,28714968,26779814,26177727,24907271,23197537,23095891,22902740,20798046,19734891,19389353,17960184,17709399,16226707,15543141,11937492,11549580,11118901,10837027,10383933,9889000,37237002,36681690,34665379,31590629,30046000,26542370,26253400,24667410,24015274,23761906,23665443,23192966,21216305,21068062,21062863,19748502,19217325,18291358,16245338,15578515,15465493,9858718,34910918,32778568,31896743,31814023,31373354,28089369,26479710,25825216,23699523,23604320,20727173,20652952,15499562,15068794,11944948,9690472,37439314,36082581,35337816,34233187,32147304,30943054,30179592,27633993,26786414,26577899,26527653,25916881,25804736,23226461,22999937,22096075,21145498,19327148,18404215,17823936,17572911,17400206,16412699,15905075,15875024,15465494,14732396,12866128,12642503,10878608,34990407,34838591,34547456,31202705,28577314,26209882,24598167,23329048,21929743,21632926,21124801,20733081,20558824,19509466,18832397,18632939,17576802,12441287,11934853,11578869,11171333,10958687,9315901,37414855,33505317,28192800,26324903,25564622,25100656,23813480,22159122,21402699,17685488,12697902,12122015,11807030,10842072,10196361,33454003,31685872,27966429,25919081,25725069,24706781,22275127,21793101,20727876,20568246,19100252,18618131,18528438,16914494,15845452,12971992,10330372,32161758,31591643,29507213,29367466,27641601,26491108,24715457,23806616,22705977,22464328,22292060,21352545,20058045,19185577,17273555,17229764,16061358,12617809,12167404,36899896,30059908,29449453,27974206,27559308,26160903,22932389,21068310,20007915,18694942,18588871,18505817,15574878,14757642,38111957,31412026,30518531,29113990,28455376,27246713,25915623,25318679,24257627,23487309,22235191,21562282,20230750,17021047,16324690,12194867,10476967,9187150,32554463,28438836,27056911,25401743,21302255,20510365,20335360,19403103,17714700,16518823,15659488,15242798,31631837,29961574,27596755,26658320,25803581,25057208,24465223,24153254,23980096,22675211,21839733,20627076,18495817,18093989,16678147,16169709,15979417,15689374,32464196,29879109,28794157,28760814,28656980,27591083,26939553,25406395,25168025,21888903,21118511,19855135,19686682,19501159,14651921,12787792,32141129,31843520,31504280,29449451,29140246,28036337,27922003,26641715,25641696,23314057,21750033,17625108,17141159,35451126,33315499,31988190,31789590,31142573,25691540,24491691,23386589,23362349,23160044,21693521,19897741,19502490,14702043,37727504,33830085,32043969,31896583,30796970,30188892,29791855,27531557,26552887,23614009,21420948,19783740,19191219,17880938,15215207,35815610,32467237,32059775,30220568,23560082,21633169,20808958,17303760,34189436,32497091,30067986,29853617,29712641,23988635,23754280,19590010,19369401,14960276,36239412,29956664,24391519,24148613,23676271,23666531,23223237,21791528,35297995,32878924,31488567,27719760,24673559,19914171,15821257,14701881,32520726,30220628,26116661,25624266,25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Year	Number of Results
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655 results

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β-cell Jagged1 is sufficient but not necessary for islet Notch activity and insulin secretory defects in obese mice.

Suda N, Bartolomé A, Liang J, Son J, Yagishita Y, Siebel C, Accili D, Ding H, Pajvani UB. Suda N, et al. Mol Metab. 2024 Mar;81:101894. doi: 10.1016/j.molmet.2024.101894. Epub 2024 Feb 3. Mol Metab. 2024. PMID: 38311286 Free PMC article.

Jagged-1 Reduces Th2 Inflammation and Memory Cell Expansion in Allergic Airway Disease.

Kimura S, Dupee Z, Lima F, Allen R, Kazmi S, Diodati N, Lukacs NW, Kunkel SL, Schaller M. Kimura S, et al. Immunohorizons. 2023 Feb 1;7(2):168-176. doi: 10.4049/immunohorizons.2300001. Immunohorizons. 2023. PMID: 36729482 Free PMC article.

Sex differences and risk factors for bleeding in Alagille syndrome.

Hankeova S, Van Hul N, Laznovsky J, Verboven E, Mangold K, Hensens N, Adori C, Verhoef E, Zikmund T, Dawit F, Kavkova M, Salplachta J, Sjöqvist M, Johansson BR, Hassan MG, Fredriksson L, Baumgärtel K, Bryja V, Lendahl U, Jheon A, Alten F, Fahnehjelm KT, Fischler B, Kaiser J, Andersson ER. Hankeova S, et al. EMBO Mol Med. 2022 Dec 7;14(12):e15809. doi: 10.15252/emmm.202215809. Epub 2022 Nov 8. EMBO Mol Med. 2022. PMID: 36345711 Free PMC article.

DUCT reveals architectural mechanisms contributing to bile duct recovery in a mouse model for Alagille syndrome.

Hankeova S, Salplachta J, Zikmund T, Kavkova M, Van Hul N, Brinek A, Smekalova V, Laznovsky J, Dawit F, Jaros J, Bryja V, Lendahl U, Ellis E, Nemeth A, Fischler B, Hannezo E, Kaiser J, Andersson ER. Hankeova S, et al. Elife. 2021 Feb 26;10:e60916. doi: 10.7554/eLife.60916. Elife. 2021. PMID: 33635272 Free PMC article.

Antisense Oligonucleotides Targeting Jagged 1 Reduce House Dust Mite-induced Goblet Cell Metaplasia in the Adult Murine Lung.

Carrer M, Crosby JR, Sun G, Zhao C, Damle SS, Kuntz SG, Monia BP, Hart CE, Grossman TR. Carrer M, et al. Am J Respir Cell Mol Biol. 2020 Jul;63(1):46-56. doi: 10.1165/rcmb.2019-0257OC. Am J Respir Cell Mol Biol. 2020. PMID: 32176858

Activation of Notch Signaling by Oocytes and Jag1 in Mouse Ovarian Granulosa Cells.

Hubbard N, Prasasya RD, Mayo KE. Hubbard N, et al. Endocrinology. 2019 Dec 1;160(12):2863-2876. doi: 10.1210/en.2019-00564. Endocrinology. 2019. PMID: 31609444 Free PMC article.

Jagged1-expressing adenovirus-infected dendritic cells induce expansion of Foxp3⁺ regulatory T cells and alleviate T helper type 2-mediated allergic asthma in mice.

Lin CL, Huang HM, Hsieh CL, Fan CK, Lee YL. Lin CL, et al. Immunology. 2019 Feb;156(2):199-212. doi: 10.1111/imm.13021. Epub 2018 Nov 29. Immunology. 2019. PMID: 30418664 Free PMC article.

Jagged1 Is Altered in Alzheimer's Disease and Regulates Spatial Memory Processing.

Marathe S, Jaquet M, Annoni JM, Alberi L. Marathe S, et al. Front Cell Neurosci. 2017 Aug 9;11:220. doi: 10.3389/fncel.2017.00220. eCollection 2017. Front Cell Neurosci. 2017. PMID: 28848392 Free PMC article.

The Notch Ligand Jagged1 Regulates the Osteoblastic Lineage by Maintaining the Osteoprogenitor Pool.

Lawal RA, Zhou X, Batey K, Hoffman CM, Georger MA, Radtke F, Hilton MJ, Xing L, Frisch BJ, Calvi LM. Lawal RA, et al. J Bone Miner Res. 2017 Jun;32(6):1320-1331. doi: 10.1002/jbmr.3106. Epub 2017 Mar 9. J Bone Miner Res. 2017. PMID: 28277610 Free PMC article.

Jagged1 expression by osteoblast-lineage cells regulates trabecular bone mass and periosteal expansion in mice.

Youngstrom DW, Dishowitz MI, Bales CB, Carr E, Mutyaba PL, Kozloff KM, Shitaye H, Hankenson KD, Loomes KM. Youngstrom DW, et al. Bone. 2016 Oct;91:64-74. doi: 10.1016/j.bone.2016.07.006. Epub 2016 Jul 12. Bone. 2016. PMID: 27416809 Free PMC article.

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