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    Biochim Biophys Acta. 1998 Mar 9;1396(2):143-7.

    Cloning and sequencing of the cDNA encoding human neurotrypsin.

    Proba K, Gschwend TP, Sonderegger P.

    Institute of Biochemistry, University of Zurich, Switzerland.

    cDNA clones encoding human neurotrypsin have been isolated from a human fetal brain cDNA library using a PCR-amplified probe. The assembled cDNA sequence contains a 2625 bp open reading frame encoding a multidomain serine protease with an overall sequence identity of 82.5% to murine neurotrypsin. Surprisingly, the human neurotrypsin exhibits an additional scavenger receptor cysteine-rich repeat.

    PMID: 9540828 [PubMed - indexed for MEDLINE]

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