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    J Virol. 1998 Mar;72(3):2010-21.

    The genome sequence of herpes simplex virus type 2.

    Dolan A, Jamieson FE, Cunningham C, Barnett BC, McGeoch DJ.

    MRC Virology Unit, Institute of Virology, Glasgow, United Kingdom. a.dolan@vir.gla.ac.uk

    The genomic DNA sequence of herpes simplex virus type 2 (HSV-2) strain HG52 was determined as 154,746 bp with a G+C content of 70.4%. A total of 74 genes encoding distinct proteins was identified; three of these were each present in two copies, within major repeat elements of the genome. The HSV-2 gene set corresponds closely with that of HSV-1, and the HSV-2 sequence prompted several local revisions to the published HSV-1 sequence (D. J. McGeoch, M. A. Dalrymple, A. J. Davison, A. Dolan, M. C. Frame, D. McNab, L. J. Perry, J. E. Scott, and P. Taylor, J. Gen. Virol. 69:1531-1574, 1988). No compelling evidence for the existence of any additional protein-coding genes in HSV-2 was identified.

    PMID: 9499055 [PubMed - indexed for MEDLINE]

    PMCID: 109494

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