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    Biochim Biophys Acta. 1993 Jul 18;1174(1):114-6.

    Human cDNA encoding DnaJ protein homologue.

    Oh S, Iwahori A, Kato S.

    Sagami Chemical Research Center, Kanagawa, Japan.

    We have cloned a cDNA encoding a DnaJ-like protein from the human fibrosarcoma HT-1080 cDNA library. This cDNA encodes a protein of 397 amino acid residues whose sequence shows 38.2% identity with the Escherichia coli DnaJ protein and 47.2% with the yeast DnaJ homologue along the entire length. Since the sequence contains the N-terminal domain region conserved in DnaJ family members and the four repeats of the Cys-X-X-Cys-X-Gly-X-Gly motif which are characteristic of DnaJ proteins, we conclude that this cDNA clone encodes the human homologue of DnaJ.

    PMID: 8334161 [PubMed - indexed for MEDLINE]

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