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    Biochim Biophys Acta. 1993 Jul 18;1174(1):111-3.

    Cloning of a unique human homologue of the Escherichia coli DNAJ heat shock protein.

    Chellaiah A, Davis A, Mohanakumar T.

    Department of Surgery and Pathology, Washington University School of Medicine, St. Louis, MO 63110.

    A human homologue of the bacterial DNAJ heatshock protein, HDJ-2, was isolated from a human umbilical vein endothelial cDNA library using a monoclonal antibody which reacts specifically to human endothelial cells and monocytes. This cDNA clone consists of 1469 nucleotides with an open reading frame of 1191 nucleotides. HDJ-2 shares significant homology with Escherichia coli heat shock protein DNAJ, as well as the yeast homologues Sec63, YDJ1, SCJ1 and SIS1. This homology suggests HDJ-2 may be involved in protein folding and/or transport.

    PMID: 8334160 [PubMed - indexed for MEDLINE]

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