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    Gene. 1994 Mar 11;140(1):127-9.

    A gene homologous to that encoding UDP galactose-4-epimerase is inducible by xylose in the yeast Pachysolen tannophilus.

    Skrzypek M, Maleszka R.

    Department of Biochemistry, University of Kentucky, Lexington 40506.

    Using DNA sequencing, we have identified a fragment of genomic DNA from Pachysolen tannophilus that is homologous to the GAL10 gene in yeasts and galE gene in bacteria, both encoding the UDP galactose-4-epimerase (EC 5.1.3.2). This gene (designated PtGAL10) is equally efficiently inducible by D-galactose (a hexose) and D-xylose (a pentose). The encoded protein shows the highest similarity to the homologous Kluyveromyces lactis protein. This includes the N-terminal domain that is not present in homologous polypeptides from other organisms.

    PMID: 8125329 [PubMed - indexed for MEDLINE]

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