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    Nucleic Acids Res. 1994 Aug 11;22(15):3151-4.

    LRG1 is expressed during sporulation in Saccharomyces cerevisiae and contains motifs similar to LIM and rho/racGAP domains.

    Müller L, Xu G, Wells R, Hollenberg CP, Piepersberg W.

    German Cancer Research Center, Heidelberg.

    We here report the sequence of a yeast gene LRG1 whose deduced amino acid sequence contains sequence motifs similar to LIM domain proteins in the amino-terminal, and to rho/rac GTPase activating proteins (rho/racGAP's) in the carboxy-terminal part. LRG1 expression is differentially regulated showing a peak of expression in sporulating cells. Gene disruption experiments indicate that the gene is not essential and may play a role during mating.

    PMID: 8065929 [PubMed - indexed for MEDLINE]

    PMCID: 310289

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