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    Gene. 1995 Apr 3;155(2):207-11.

    Structure, sequence and location of the UQCRFS1 gene for the human Rieske Fe-S protein.

    Pennacchio LA, Bergmann A, Fukushima A, Okubo K, Salemi A, Lennon GG.

    Human Genome Center, Lawrence Livermore National Laboratory, Livermore, CA 94550, USA.

    We have identified and studied the chromosomal location of the human Rieske Fe-S protein-encoding gene UQCRFS1. Mapping by hybridization to a panel of monochromosomal hybrid cell lines indicated that a UQCRFS1 partial cDNA was derived from either chromosome 19 or 22. By screening a human chromosome 19 specific genomic cosmid library with a probe from this cDNA sequence, we identified a corresponding cosmid. Portions of this cosmid were sequenced directly. The exon, exon:intron junction and flanking sequences verified that this cosmid contains the genomic locus. Fluorescent in situ hybridization (FISH) was performed to localize this cosmid to chromosome band 19q12.

    PMID: 7721092 [PubMed - indexed for MEDLINE]

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