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    Gene. 1985;37(1-3):191-7.

    Structure of the chromosomal gene for human serum prealbumin.

    Sasaki H, Yoshioka N, Takagi Y, Sakaki Y.

    The human prealbumin gene has been cloned and its complete nucleotide sequence determined. The gene has a size of about 6.9 kb and is composed of four exons and three introns. Two Alu family sequences having opposing polarity were found in introns. In the 5'-flanking region, we found two overlapping sequences which have extensive homology to the glucocorticoid-responsive element. Three sequences identical with the enhancer core sequence were identified in introns and the 3'-flanking region. Unusual tandem repeats of a sequence, TTTTG, were also found in the 5'-flanking region and introns.

    PMID: 4054629 [PubMed - indexed for MEDLINE]

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