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    Nature. 1985 May 2-8;315(6014):37-40.

    Three-dimensional structure of calmodulin.

    Babu YS, Sack JS, Greenhough TJ, Bugg CE, Means AR, Cook WJ.

    The three-dimensional structure of calmodulin has been determined crystallographically at 3.0 A resolution. The molecule consists of two globular lobes connected by a long exposed alpha-helix. Each lobe binds two calcium ions through helix-loop-helix domains similar to those of other calcium-binding proteins. The long helix between the lobes may be involved in interactions of calmodulin with drugs and various proteins.

    PMID: 3990807 [PubMed - indexed for MEDLINE]

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