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    Nature. 1988 Dec 8;336(6199):551-7.

    A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homoeobox protein.

    Scheidereit C, Cromlish JA, Gerster T, Kawakami K, Balmaceda CG, Currie RA, Roeder RG.

    Laboratory of Biochemistry and Molecular Biology, Rockefeller University, New York, New York 10021.

    The human lymphoid-specific transcription factor OTF-2 contains a homoeodomain that is required for DNA binding and binds specifically to DNA elements that are recognized by Drosophila homoeodomain proteins, suggesting coevolutionary relationships between mammalian and invertebrate homoeodomain proteins and their DNA recognition elements.

    PMID: 2904654 [PubMed - indexed for MEDLINE]

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