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    Biochem Biophys Res Commun. 1988 Aug 30;155(1):524-9.

    Structure of a novel human granulocyte peptide with anti-ACTH activity.

    Singh A, Bateman A, Zhu QZ, Shimasaki S, Esch F, Solomon S.

    Royal Victoria Hospital, Department of Medicine, Montreal, Quebec, Canada.

    We report the purification, structure and biological properties of a peptide of novel sequence from human granulocytes that inhibits ACTH stimulated synthesis of corticosterone in rat adrenal cell suspensions. The peptide HP-4 is homologous to a previously described human granulocyte peptide HP-1 that has no anti-ACTH activity.

    PMID: 2843187 [PubMed - indexed for MEDLINE]

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