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    J Biochem. 1989 May;105(5):676-9.

    Cloning and characterization of bovine cytochrome P-450(11 beta) genes.

    Hashimoto T, Morohashi K, Omura T.

    Department of Molecular Biology, Graduate School of Medical Science, Kyushu University, Fukuoka.

    We isolated 4 different clones of the P-450(11 beta) gene from a bovine genomic library. These genomic clones were highly homologous with each other. Two of the isolated clones were pseudogenes. Determination of its nucleotide sequences indicated that the bovine P-450(11 beta) gene is divided into 9 exons by 8 introns and that it is about 8.5 kb in total length. The number of exons and the locations of intron insertion into the P-450(11 beta) gene are identical with those in the case of P-450(SCC), but different from those of other microsomal P-450s.

    PMID: 2753866 [PubMed - indexed for MEDLINE]

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