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    Gene. 1989 Dec 7;84(1):91-104.

    The nucleotide sequence of a mouse renin-encoding gene, Ren-1d, and its upstream region.

    Burt DW, Mullins LJ, George H, Smith G, Brooks J, Pioli D, Brammar WJ.

    Department of Biochemistry, University of Leicester, U.K.

    The renin-encoding genes have been cloned from high (Ren-1d, Ren-2d)- and low (Ren-1c)-renin-producing strains of mice (DBA/2J and C57BL/10). Each of the genes is approx. 9.6 kb in length and consists of nine exons and eight introns. The entire nucleotide sequence of the Ren-1d gene has been determined and the 5'-flanking regions of the three genes, Ren-1c, Ren-1d and Ren-2d, have been compared. The significance of several potential regulatory signals found in the DNA is discussed.

    PMID: 2691339 [PubMed - indexed for MEDLINE]

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