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    Hum Genet. 1989 Jan;81(2):171-4.

    The human cytochrome P450 CYP3 locus: assignment to chromosome 7q22-qter.

    Spurr NK, Gough AC, Stevenson K, Wolf CR.

    Human Genetic Resources, Imperial Cancer Research Fund, Clare Hall Laboratories, Herts, UK.

    The cytochrome P-450s are a large multigene family of enzymes involved in the metabolism and detoxification of drugs and chemicals. Using a full length cDNA clone for the human nifedipine oxidase gene (CYP3) and a panel of human-rodent somatic cell hybrids, we have assigned this gene family to chromosome 7q22-qter. A search for RFLPs using this probe yielded no results.

    PMID: 2563251 [PubMed - indexed for MEDLINE]

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