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    FEBS Lett. 1989 Feb 27;244(2):481-3.

    Family of human Na+,K+-ATPase genes. Structure of the putative regulatory region of the alpha+-gene.

    Sverdlov ED, Bessarab DA, Malyshev IV, Petrukhin KE, Smirnov YuV, Ushkaryov YuA, Monastyrskaya GS, Broude NE, Modyanov NN.

    Shemyakin Institute of Bioorganic Chemistry, USSR Academy of Sciences, Moscow.

    The primary structure of the putative regulatory region of a gene of the Na+,K+-ATPase multigene family in the human genome has been determined. This region includes the first exon with all of the untranslatable sequence of mRNA and a dozen nucleotides, coding for the first four amino acids of the hypothetic precursor of the alpha+-subunit. The entire region comprises over 1400 bp. The possible role of specific nucleotide blocks within this region in comparison with other genes is discussed.

    PMID: 2537767 [PubMed - indexed for MEDLINE]

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