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    Biochim Biophys Acta. 1991 Aug 27;1090(1):1-8.

    Molecular cloning of the murine ST2 gene. Characterization and chromosomal mapping.

    Tominaga S, Jenkins NA, Gilbert DJ, Copeland NG, Tetsuka T.

    Department of Biochemistry II, Jichi Medical School, Tochigi, Japan.

    The genomic locus of the murine ST2 gene was isolated based on homology with a murine ST2 complementary DNA sequence and its complete nucleotide sequence was determined. The locus is composed of eight exons and seven introns and is approx. 9 kilobase pairs in size. Two Sp1 binding sites are present in the 5' flanking region. The murine ST2 gene, which was expressed only in the growth-stimulated BALB/c-3T3 cells, was mapped to mouse chromosome one, very tightly linked to the interleukin 1 receptor-type 1 locus.

    PMID: 1832015 [PubMed - indexed for MEDLINE]

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