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    Genomics. 1991 Jun;10(2):441-8.

    Chromosomal localization of the human annexin III (ANX3) gene.

    Tait JF, Frankenberry DA, Miao CH, Killary AM, Adler DA, Disteche CM.

    Department of Laboratory Medicine, University of Washington, Seattle 98195.

    The annexins or lipocortins are a new family of calcium-dependent phospholipid-binding proteins. Annexin III has been previously identified as inositol 1,2-cyclic phosphate 2-phosphohydrolase (EC 3.1.4.36), an enzyme of inositol phosphate metabolism, and also as placental anticoagulant protein III, lipocortin III, calcimedin 35-alpha, and an abundant neutrophil cytoplasmic protein. In this study, the gene (ANX3) encoding annexin III was localized to human chromosome 4 at band q21 (q13-q22) by (1) polymerase chain reaction analysis of a human-rodent hybrid cell panel, confirmed by genomic Southern blot analysis of the same panel with a cDNA probe and (2) in situ hybridization with a cDNA probe.

    PMID: 1830024 [PubMed - indexed for MEDLINE]

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