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    Appl Environ Microbiol. 2006 Aug;72(8):5670-2.

    Production of resveratrol in recombinant microorganisms.

    Beekwilder J, Wolswinkel R, Jonker H, Hall R, de Vos CH, Bovy A.

    Plant Research International, 6700 AA Wageningen, The Netherlands. Jules.Beekwilder@wur.nl

    Resveratrol production in Saccharomyces cerevisiae was compared to that in Escherichia coli. In both systems, 4-coumarate:coenzyme A ligase from tobacco and stilbene synthase from grapes were expressed. When p-coumaric acid was used as the precursor, resveratrol accumulations in the culture medium were observed to be comparable in E. coli (16 mg/liter) and yeast (6 mg/liter).

    PMID: 16885328 [PubMed - indexed for MEDLINE]

    PMCID: 1538726

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