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    Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1218-22. Epub 2002 Jan 22.

    Structural basis of transcription: alpha-amanitin-RNA polymerase II cocrystal at 2.8 A resolution.

    Bushnell DA, Cramer P, Kornberg RD.

    Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305-5126, USA.

    The structure of RNA polymerase II in a complex with the inhibitor alpha-amanitin has been determined by x-ray crystallography. The structure of the complex indicates the likely basis of inhibition and gives unexpected insight into the transcription mechanism.

    PMID: 11805306 [PubMed - indexed for MEDLINE]

    PMCID: 122170

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