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    Biochim Biophys Acta. 2000 Apr 25;1491(1-3):355-63.

    Characterization of JDP genes, an evolutionarily conserved J domain-only protein family, from human and moths.

    Lee J, Hahn Y, Yun JH, Mita K, Chung JH.

    Department of Biological Sciences, Korea Advanced Institute of Science and Technology, Taejon, South Korea.

    We characterized evolutionarily conserved J domain containing protein (JDP) genes from human, Bombyx mori, and Manduca sexta. Each of the JDP proteins contains a J domain at its N-terminus and a highly conserved C-terminal domain. Southern blot analysis revealed that the human JDP1 gene is present as a single copy in the human genome. Expression was higher in brain, heart, and testis than in kidney or stomach. Human JDP1 was mapped in silico to chromosome 10q21.1, which exhibits a conserved synteny with the central region of mouse chromosome 10. Drosophila jdp is located at 99F4-99F11 on the right arm of the third chromosome.

    PMID: 10760603 [PubMed - indexed for MEDLINE]

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