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    Mech Dev. 1998 Dec;79(1-2):161-4.

    A transcription unit at the ken and barbie gene locus encodes a novel Drosophila zinc finger protein.

    Kühnlein RP, Chen CK, Schuh R.

    Max-Planck-Institut für biophysikalische Chemie, Abt. Molekulare Entwicklungsbiologie, Göttingen, Germany.

    We describe a novel Drosophila transcription unit, located in chromosome region 60A. It encodes a zinc finger protein that is expressed in distinct spatial and temporal patterns during embryogenesis. Its initial expression occurs in a stripe at the anterior and the posterior trunk boundary, respectively. The two stripes are activated and spatially controlled by gap-gene activities. The P-element of the enhancer trap line l(2)02970 is inserted in the 5'-region of the transcript and causes a ken and barbie (ken) phenotype, associated with malformation of male genital structures.

    PMID: 10349629 [PubMed - indexed for MEDLINE]

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