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    Results: 1 to 20 of 39

    1.

    Syntheses of novel high affinity ligands for opioid receptors.

    Wentland MP, Lou R, Lu Q, Bu Y, Denhardt C, Jin J, Ganorkar R, VanAlstine MA, Guo C, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2009 Apr 15;19(8):2289-94. Epub 2009 Feb 25.PMID: 19282177 [PubMed - indexed for MEDLINE]Related articles

    2.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 7: syntheses and opioid receptor properties of cyclic variants of cyclazocine.

    Wentland MP, Lu Q, Ganorkar R, Zhang SZ, Jo S, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2009 Jan 15;19(2):365-8. Epub 2008 Nov 24.PMID: 19091564 [PubMed - indexed for MEDLINE]Related articles

    3.

    Syntheses and opioid receptor binding properties of carboxamido-substituted opioids.

    Wentland MP, Lou R, Lu Q, Bu Y, VanAlstine MA, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2009 Jan 1;19(1):203-8. Epub 2008 Nov 7.PMID: 19027293 [PubMed - indexed for MEDLINE]Related articles

    4.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 6: Opioid receptor binding properties of cyclic variants of 8-carboxamidocyclazocine.

    Wentland MP, Sun X, Cohen DJ, Bidlack JM.

    Bioorg Med Chem. 2008 May 15;16(10):5653-64. Epub 2008 Mar 30.PMID: 18417347 [PubMed - indexed for MEDLINE]Related articlesFree article

    5.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 5. Opioid receptor binding properties of N-((4'-phenyl)-phenethyl) analogues of 8-CAC.

    VanAlstine MA, Wentland MP, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2007 Dec 1;17(23):6516-20. Epub 2007 Sep 29.PMID: 17935988 [PubMed - indexed for MEDLINE]Related articlesFree article

    6.

    CC12, a high-affinity ligand for [3H]cimetidine binding, is an improgan antagonist.

    Hough LB, Nalwalk JW, Phillips JG, Kern B, Shan Z, Wentland MP, de Esch IJ, Janssen E, Barr T, Stadel R.

    Neuropharmacology. 2007 Apr;52(5):1244-55. Epub 2007 Jan 20.PMID: 17336343 [PubMed - indexed for MEDLINE]Related articlesFree article

    7.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. 4. Opioid receptor binding properties of 8-[N-(4'-phenyl)-phenethyl)carboxamido] analogues of cyclazocine and ethylketocycalzocine.

    Wentland MP, VanAlstine M, Kucejko R, Lou R, Cohen DJ, Parkhill AL, Bidlack JM.

    J Med Chem. 2006 Sep 7;49(18):5635-9.PMID: 16942039 [PubMed - indexed for MEDLINE]Related articles

    8.

    Antinociceptive, brain-penetrating derivatives related to improgan, a non-opioid analgesic.

    Hough LB, Nalwalk JW, Lu Q, Shan Z, Svokos K, Wentland MP, Montero MJ.

    Eur J Pharmacol. 2005 Oct 17;522(1-3):38-46. Epub 2005 Oct 10.PMID: 16216240 [PubMed - indexed for MEDLINE]Related articles

    9.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 3: 8-Thiocarboxamido and 8-thioformamido derivatives of cyclazocine.

    Wentland MP, Sun X, Bu Y, Lou R, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2005 May 16;15(10):2547-51.PMID: 15863314 [PubMed - indexed for MEDLINE]Related articles

    10.

    Synthesis and opioid receptor binding properties of a highly potent 4-hydroxy analogue of naltrexone.

    Wentland MP, Lu Q, Lou R, Bu Y, Knapp BI, Bidlack JM.

    Bioorg Med Chem Lett. 2005 Apr 15;15(8):2107-10.PMID: 15808478 [PubMed - indexed for MEDLINE]Related articles

    11.

    Effects of the mixed-action kappa/mu opioid agonist 8-carboxamidocyclazocine on cocaine- and food-maintained responding in rhesus monkeys.

    Stevenson GW, Wentland MP, Bidlack JM, Mello NK, Negus SS.

    Eur J Pharmacol. 2004 Dec 15;506(2):133-41.PMID: 15588733 [PubMed - indexed for MEDLINE]Related articles

    12.

    Kappa-opioid receptor ligands inhibit cocaine-induced HIV-1 expression in microglial cells.

    Gekker G, Hu S, Wentland MP, Bidlack JM, Lokensgard JR, Peterson PK.

    J Pharmacol Exp Ther. 2004 May;309(2):600-6. Epub 2004 Feb 2.PMID: 14757849 [PubMed - indexed for MEDLINE]Related articlesFree article

    13.

    Synthesis and pharmacology of 8-amino-3-[(tetrahydro-2-furanyl)methyl] benzomorphan.

    Zhou Q, Duan WH, Cohen DJ, Bidlack JM, Wentland MP.

    Yao Xue Xue Bao. 2003 Oct;38(10):748-53.PMID: 14730897 [PubMed - indexed for MEDLINE]Related articles

    14.

    10-Ketomorphinan and 3-substituted-3-desoxymorphinan analogues as mixed kappa and micro opioid ligands: synthesis and biological evaluation of their binding affinity at opioid receptors.

    Zhang A, Xiong W, Bidlack JM, Hilbert JE, Knapp BI, Wentland MP, Neumeyer JL.

    J Med Chem. 2004 Jan 1;47(1):165-74.PMID: 14695830 [PubMed - indexed for MEDLINE]Related articles

    15.

    Redefining the structure-activity relationships of 2,6-methano-3-benzazocines. Part 2: 8-formamidocyclazocine analogues.

    Wentland MP, Sun X, Ye Y, Lou R, Bidlack JM.

    Bioorg Med Chem Lett. 2003 Jun 2;13(11):1911-4.PMID: 12749896 [PubMed - indexed for MEDLINE]Related articles

    16.

    Syntheses and opioid receptor binding affinities of 8-amino-2,6-methano-3-benzazocines.

    Wentland MP, Ye Y, Cioffi CL, Lou R, Zhou Q, Xu G, Duan W, Dehnhardt CM, Sun X, Cohen DJ, Bidlack JM.

    J Med Chem. 2003 Feb 27;46(5):838-49.PMID: 12593663 [PubMed - indexed for MEDLINE]Related articles

    17.

    8-Carboxamidocyclazocine: a long-acting, novel benzomorphan.

    Bidlack JM, Cohen DJ, McLaughlin JP, Lou R, Ye Y, Wentland MP.

    J Pharmacol Exp Ther. 2002 Jul;302(1):374-80.PMID: 12065740 [PubMed - indexed for MEDLINE]Related articlesFree article

    18.

    3-Carboxamido analogues of morphine and naltrexone. synthesis and opioid receptor binding properties.

    Wentland MP, Lou R, Dehnhardt CM, Duan W, Cohen DJ, Bidlack JM.

    Bioorg Med Chem Lett. 2001 Jul 9;11(13):1717-21.PMID: 11425545 [PubMed - indexed for MEDLINE]Related articles

    19.

    8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines.

    Wentland MP, Lou R, Ye Y, Cohen DJ, Richardson GP, Bidlack JM.

    Bioorg Med Chem Lett. 2001 Mar 12;11(5):623-6.PMID: 11266156 [PubMed - indexed for MEDLINE]Related articles

    20.

    Selective protection and functionalization of morphine: synthesis and opioid receptor binding properties of 3-amino-3-desoxymorphine derivatives.

    Wentland MP, Duan W, Cohen DJ, Bidlack JM.

    J Med Chem. 2000 Sep 21;43(19):3558-65.PMID: 11000010 [PubMed - indexed for MEDLINE]Related articles

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