PubMed

Interaction of drugs of abuse and maintenance treatments with human P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2).

Tournier N, Chevillard L, Megarbane B, Pirnay S, Scherrmann JM, Declèves X.

Int J Neuropsychopharmacol. 2009 Nov 4:1-11. [Epub ahead of print]PMID: 19887017 [PubMed - as supplied by publisher]Related articles

Influence of Development, HIV Infection, and Antiretroviral Therapies on the Gene Expression Profiles of ABC Transporters in Human Lymphocytes.

Giraud C, Manceau S, Declèves X, Goffinet F, Morini JP, Chappuy H, Batteux F, Chouzenoux S, Yousif S, Scherrmann JM, Blanche S, Tréluyer JM.

J Clin Pharmacol. 2009 Oct 16. [Epub ahead of print]PMID: 19837908 [PubMed - as supplied by publisher]Related articles

Sprague-Dawley rats display sex-linked differences in the pharmacokinetics of 3,4-methylenedioxymethamphetamine (MDMA) and its metabolite 3,4-methylenedioxyamphetamine (MDA).

Fonsart J, Menet MC, Debray M, Hirt D, Noble F, Scherrmann JM, Declèves X.

Toxicol Appl Pharmacol. 2009 Dec 15;241(3):339-47. Epub 2009 Sep 23.PMID: 19781562 [PubMed - in process]Related articles

Pharmacology of morphine in obese patients: clinical implications.

Lloret Linares C, Declèves X, Oppert JM, Basdevant A, Clement K, Bardin C, Scherrmann JM, Lepine JP, Bergmann JF, Mouly S.

Clin Pharmacokinet. 2009;48(10):635-51. doi: 10.2165/11317150-000000000-00000.PMID: 19743886 [PubMed - in process]Related articles

Ibogaine labeling with 99mTc-tricarbonyl: synthesis and transport at the mouse blood-brain barrier.

Tournier N, André P, Blondeel S, Rizzo-Padoin N, du Moulinet d'Hardemarre A, Declèves X, Scherrmann JM, Cisternino S.

J Pharm Sci. 2009 Dec;98(12):4650-60.PMID: 19492342 [PubMed - in process]Related articles

Xenobiotic-metabolizing enzymes and transporters in the normal human brain: regional and cellular mapping as a basis for putative roles in cerebral function.

Dutheil F, Dauchy S, Diry M, Sazdovitch V, Cloarec O, Mellottée L, Bièche I, Ingelman-Sundberg M, Flinois JP, de Waziers I, Beaune P, Declèves X, Duyckaerts C, Loriot MA.

Drug Metab Dispos. 2009 Jul;37(7):1528-38. Epub 2009 Apr 9.PMID: 19359404 [PubMed - indexed for MEDLINE]Related articles

Development of an optimized procedure for the preparation of rat intestinal microsomes: comparison of hepatic and intestinal microsomal cytochrome P450 enzyme activities in two rat strains.

Bruyère A, Declevès X, Bouzom F, Proust L, Martinet M, Walther B, Parmentier Y.

Xenobiotica. 2009 Jan;39(1):22-32.PMID: 19219745 [PubMed - indexed for MEDLINE]Related articles

ABC transporters, cytochromes P450 and their main transcription factors: expression at the human blood-brain barrier.

Dauchy S, Dutheil F, Weaver RJ, Chassoux F, Daumas-Duport C, Couraud PO, Scherrmann JM, De Waziers I, Declèves X.

J Neurochem. 2008 Dec;107(6):1518-28.PMID: 19094056 [PubMed - indexed for MEDLINE]Related articles

Expression and transcriptional regulation of ABC transporters and cytochromes P450 in hCMEC/D3 human cerebral microvascular endothelial cells.

Dauchy S, Miller F, Couraud PO, Weaver RJ, Weksler B, Romero IA, Scherrmann JM, De Waziers I, Declèves X.

Biochem Pharmacol. 2009 Mar 1;77(5):897-909. Epub 2008 Nov 12.PMID: 19041851 [PubMed - indexed for MEDLINE]Related articles

High levels of P-glycoprotein activity in human lymphocytes in the first 6 months of life.

Giraud C, Declèves X, Perrot JY, Manceau S, Pannier E, Firtion G, Morini JP, Chappuy H, Batteux F, Chouzenoux S, Scherrmann JM, Blanche S, Tréluyer JM.

Clin Pharmacol Ther. 2009 Mar;85(3):289-95. Epub 2008 Nov 26.PMID: 19037199 [PubMed - indexed for MEDLINE]Related articles

Effect of chronic exposure to morphine on the rat blood-brain barrier: focus on the P-glycoprotein.

Yousif S, Saubaméa B, Cisternino S, Marie-Claire C, Dauchy S, Scherrmann JM, Declèves X.

J Neurochem. 2008 Nov;107(3):647-57. Epub 2008 Aug 30.PMID: 18761714 [PubMed - indexed for MEDLINE]Related articles

Buprenorphine alters desmethylflunitrazepam disposition and flunitrazepam toxicity in rats.

Pirnay S, Megarbane B, Declèves X, Risède P, Borron SW, Bouchonnet S, Perrin B, Debray M, Milan N, Duarte T, Ricordel I, Baud FJ.

Toxicol Sci. 2008 Nov;106(1):64-73. Epub 2008 Aug 14.PMID: 18703559 [PubMed - indexed for MEDLINE]Related articlesFree article

Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice.

Reddy LH, Khoury H, Paci A, Deroussent A, Ferreira H, Dubernet C, Declèves X, Besnard M, Chacun H, Lepêtre-Mouelhi S, Desmaële D, Rousseau B, Laugier C, Cintrat JC, Vassal G, Couvreur P.

Drug Metab Dispos. 2008 Aug;36(8):1570-7. Epub 2008 May 12.PMID: 18474674 [PubMed - indexed for MEDLINE]Related articlesFree article

Sprague-Dawley rats display metabolism-mediated sex differences in the acute toxicity of 3,4-methylenedioxymethamphetamine (MDMA, ecstasy).

Fonsart J, Menet MC, Declèves X, Galons H, Crété D, Debray M, Scherrmann JM, Noble F.

Toxicol Appl Pharmacol. 2008 Jul 1;230(1):117-25. Epub 2008 Feb 15.PMID: 18358511 [PubMed - indexed for MEDLINE]Related articles

ABC transporters and the accumulation of imatinib and its active metabolite CGP74588 in rat C6 glioma cells.

Declèves X, Bihorel S, Debray M, Yousif S, Camenisch G, Scherrmann JM.

Pharmacol Res. 2008 Mar;57(3):214-22. Epub 2008 Feb 2.PMID: 18337118 [PubMed - indexed for MEDLINE]Related articles

A functional in vitro model of rat blood-brain barrier for molecular analysis of efflux transporters.

Perrière N, Yousif S, Cazaubon S, Chaverot N, Bourasset F, Cisternino S, Declèves X, Hori S, Terasaki T, Deli M, Scherrmann JM, Temsamani J, Roux F, Couraud PO.

Brain Res. 2007 May 30;1150:1-13. Epub 2007 Mar 12.PMID: 17434463 [PubMed - indexed for MEDLINE]Related articles

Case report: quantification of methadone-induced respiratory depression using toxicokinetic/toxicodynamic relationships.

Mégarbane B, Declèves X, Bloch V, Bardin C, Chast F, Baud FJ.

Crit Care. 2007;11(1):R5.PMID: 17224045 [PubMed - indexed for MEDLINE]Related articlesFree article

Expression of drug transporters at the blood-brain barrier using an optimized isolated rat brain microvessel strategy.

Yousif S, Marie-Claire C, Roux F, Scherrmann JM, Declèves X.

Brain Res. 2007 Feb 23;1134(1):1-11. Epub 2006 Dec 28.PMID: 17196184 [PubMed - indexed for MEDLINE]Related articles

Is P-glycoprotein (ABCB1) a phase 0 or a phase 3 colchicine transporter depending on colchicine exposure conditions?

Declèves X, Niel E, Debray M, Scherrmann JM.

Toxicol Appl Pharmacol. 2006 Dec 1;217(2):153-60. Epub 2006 Aug 10.PMID: 16978677 [PubMed - indexed for MEDLINE]Related articles

Role of ABC transporters in the chemoresistance of human gliomas.

Declèves X, Amiel A, Delattre JY, Scherrmann JM.

Curr Cancer Drug Targets. 2006 Aug;6(5):433-45. Review.PMID: 16918310 [PubMed - indexed for MEDLINE]Related articles