Fenclonine

A selective and irreversible inhibitor of tryptophan hydroxylase, a rate-limiting enzyme in the biosynthesis of serotonin (5-HYDROXYTRYPTAMINE). Fenclonine acts pharmacologically to deplete endogenous levels of serotonin.

Year introduced: 1993(1971)

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Do not include MeSH terms found below this term in the MeSH hierarchy.

Tree Number(s): D12.125.072.050.685.440

MeSH Unique ID: D010134

Registry Number: R5J7E3L9SP

Entry Terms:

• para-Chlorophenylalanine
• para Chlorophenylalanine
• p-Chlorophenylalanine
• DL-3-(4-Chlorophenyl)alanine
• Fenclonin
• Fenclonine, (D)-Isomer
• Fenclonine Hydrobromide
• Hydrobromide, Fenclonine
• Fenclonine Hydrochloride
• Hydrochloride, Fenclonine
• CP-10,188
• Fenclonine (L)-Isomer

Previous Indexing:

• Phenylalanine (1966-1970)

Pharmacologic Action:

• Enzyme Inhibitors
• Serotonin Antagonists

All MeSH Categories
Chemicals and Drugs Category
Amino Acids, Peptides, and Proteins
Amino Acids
Amino Acids, Cyclic
Amino Acids, Aromatic
Phenylalanine
Fenclonine