1: SEC22B SEC22 vesicle trafficking protein homolog B (S. cerevisiae) [ Homo sapiens ]

GeneID: 9554 updated 8-Nov-2009

[Top][Help]Summary

Official Symbol
SEC22Bprovided by HGNC
Official Full Name
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)provided by HGNC
Primary Source
HGNC:10700
See related
Ensembl:ENSG00000223380; HPRD:04939; MIM:604029
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
ERS-24; SEC22L1; SEC22B
Summary
The protein encoded by this gene is a member of the SEC22 family of vesicle trafficking proteins. It seems to complex with SNARE and it is thought to play a role in the ER-Golgi protein trafficking. This protein has strong similarity to Mus musculus and Cricetulus griseus proteins.

[Top][Help]Genomic regions, transcripts, and products

(plus) Go to reference sequence detailsTry our new Sequence Viewer


[Top][Help]Bibliography

Related Articles in PubMed

[Top][Help]Interactions

Description ..........
  Product Interactant Other Gene Complex Source Pubs          
 
  NP_004883.1   Syntaxin 5A   STX5      HPRD    PubMed
Affinity Capture-MS; Affinity Capture-Western
  BioGRID:114926   BioGRID:119782   STX18      BioGRID    PubMed
Affinity Capture-Western
  BioGRID:114926   BioGRID:112680   STX5      BioGRID    PubMed

[Top][Help]General gene information

Markers

RH45098(e-PCR)
Links: UniSTS:91882

Homology

Homologs of the SEC22B gene The SEC22B gene is conserved in dog, cow, mouse, rat, zebrafish, fruit fly, mosquito, C.elegans, S.pombe, S.cerevisiae, K.lactis, E.gossypii, M.grisea, N.crassa, A.thaliana, rice, and P.falciparum.


Map Viewer (Mouse, Rat)

Pathways

KEGG pathway: SNARE interactions in vesicular transport
04130

Gene Ontology Provided by GOA

Function Evidence
protein binding IPI PubMed

[Top][Help]General protein information

Preferred Names
SEC22 vesicle trafficking protein homolog B
Names
SEC22 vesicle trafficking protein homolog B
OTTHUMP00000205451
SEC22 vesicle trafficking protein-like 1
SEC22, vesicle trafficking protein-like 1

[Top][Help]NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

mRNA and Protein(s)

  1. NM_004892.4NP_004883.2  SEC22 vesicle trafficking protein homolog B

    Source sequence(s)
    BC001364,CD619408,CR624978
    Consensus CDS
    CCDS44206.1
    UniProtKB/Swiss-Prot
    O75396
    Conserved Domains (1) summary
    COG5143
    Location:10161
    Blast Score: 190
    SNC1; Synaptobrevin/VAMP-like protein [Intracellular trafficking and secretion]

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

  1. NC_000001.10

    Range
    145096406..145116921
    Download
    GenBank FASTA Sequence Viewer (Graphics)
  2. NT_167185.1 

    Range
    423993..444508
    Download
    GenBank FASTA Sequence Viewer (Graphics)

[Top][Help]Related Sequences

  Nucleotide   Protein
  genomic   AL359758.15  (2000..19898)   None
  genomic   BX537145.3  (5477..8144)   None
  mRNA   AF047442.1   AAC39893.1
  mRNA   AI085383.1   None
  mRNA   AK289875.1   BAF82564.1
  mRNA   BC001364.2   AAH01364.1
  mRNA   CD619408.1   None
  mRNA   CR624978.1   None
  other-genetic   DQ892584.2   ABM83510.1
  other-genetic   DQ895801.2   ABM86727.1
Protein Accession   Links
O75396.3   GenPept   UniProtKB/Swiss-Prot:O75396

[Top][Help]Additional Links

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.