Rhox12 reproductive homeobox 12 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rhox12provided by MGI
Official Full Name: reproductive homeobox 12provided by MGI
Primary source: MGI:MGI:2685994
See related: Ensembl:ENSMUSG00000071766 AllianceGenome:MGI:2685994
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Gm1148
Summary: Predicted to enable sequence-specific double-stranded DNA binding activity. Predicted to be involved in positive regulation of gene expression. Predicted to be located in cytosol and nucleoplasm. Orthologous to human RHOXF1 (Rhox homeobox family member 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Restricted expression toward placenta adult (RPKM 16.2) See more
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Genomic context

Location:: X A3.3; X 22.36 cM

Exon count:: 4

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (37192939..37199784, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (38104062..38110907, complement)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IBA Inferred from Biological aspect of Ancestor more info
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in regulation of transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: reproductive homeobox on X chromosome, 12

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001025083.2 → NP_001020254.1 reproductive homeobox on X chromosome, 12

See identical proteins and their annotated locations for NP_001020254.1

Status: VALIDATED

Source sequence(s)

BU757254, DQ058649

Consensus CDS

CCDS30087.1

UniProtKB/TrEMBL

Q4TU81, V9GXS9

Related

ENSMUSP00000094191.5, ENSMUST00000096453.12

Conserved Domains (1) summary

cd00086
Location:107 → 169

homeodomain; Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.