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    His2B:CG33884 [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3772575, updated on 29-Dec-2023

    Summary

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    Official Symbol
    His2B:CG33884provided by FlyBase
    Primary source
    FLYBASE:FBgn0053884
    Locus tag
    Dmel_CG33884
    See related
    AllianceGenome:FB:FBgn0053884
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG33884; Dmel\CG33884
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in chromatin assembly or disassembly. Predicted to be part of nucleosome. Orthologous to several human genes including H2BC11 (H2B clustered histone 11); H2BC12 (H2B clustered histone 12); and H2BC13 (H2B clustered histone 13). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

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    See His2B:CG33884 in Genome Data Viewer
    Location:
    39D5-39D5; 2-54 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (21497745..21498339, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (21497745..21498339, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene histone H3 Neighboring gene histone H1 Neighboring gene histone H2A Neighboring gene small non-coding RNA 430l Neighboring gene histone H4

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Sequence of histone 2B of Drosophila melanogaster. Elgin SC, et al. Biochemistry, 1979 Dec 11. PMID 117830
    2. Acetylation by Tip60 is required for selective histone variant exchange at DNA lesions. Kusch T, et al. Science, 2004 Dec 17. PMID 15528408
    3. Histone H2A.Z is widely but nonrandomly distributed in chromosomes of Drosophila melanogaster. Leach TJ, et al. J Biol Chem, 2000 Jul 28. PMID 10801889
    4. The Release 6 reference sequence of the Drosophila melanogaster genome. Hoskins RA, et al. Genome Res, 2015 Mar. PMID 25589440, Free PMC Article
    5. Sequence finishing and mapping of Drosophila melanogaster heterochromatin. Hoskins RA, et al. Science, 2007 Jun 15. PMID 17569867, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables DNA binding NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    enables protein heterodimerization activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables structural constituent of chromatin IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in chromatin organization ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of nucleosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nucleosome NAS
    Non-traceable Author Statement
    more info
    		 PubMed 
    part_of nucleosome TAS
    Traceable Author Statement
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    histone H2B
    Names
    CG33884-PA
    His2B:CG33884-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      21497745..21498339 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001032174.2 → NP_001027345.1  histone H2B [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001027345.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P02283, Q4ABE1, Q9W5U7
      Conserved Domains (1) summary
      smart00427
      Location:33 → 121
      H2B; Histone H2B
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    6PWE_D.1
    6PWE_H.1
    6PWF_D.1
    6PWF_H.1
    P02283.2 P02283

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