Official Symbol

UBA2provided by HGNC

Official Full Name

ubiquitin-like modifier activating enzyme 2provided by HGNC

Primary Source

HGNC:30661

See related

Ensembl:ENSG00000126261; HPRD:11658

Gene type

protein coding

RefSeq status

VALIDATED

Organism

Homo sapiens

Lineage

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo

Also known as

ARX; SAE2; FLJ13058; HRIHFB2115; UBA2

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Preferred Names

SUMO-1 activating enzyme subunit 2

Names

SUMO-1 activating enzyme subunit 2

SUMO1 activating enzyme subunit 2

anthracycline-associated resistance

UBA2, ubiquitin-activating enzyme E1 homolog

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_005499.2 → NP_005490.1  SUMO-1 activating enzyme subunit 2

   Source sequence(s)

   AF090384,BC003153,BG503066,BG678201,BM556031,U35832

   Consensus CDS

   CCDS12439.1

   UniProtKB/Swiss-Prot

   Q9UBT2

   Conserved Domains (2) summary

   cd01489
   Location:30 – 200
   Blast Score: 860

   Uba2_SUMO; Ubiquitin activating enzyme (E1) subunit UBA2. UBA2 is part of the heterodimeric activating enzyme (E1), specific for the SUMO family of ubiquitin-like proteins (Ubls). E1 enzymes are part of a conjugation cascade to attach Ub or Ubls, covalently to...

   cl00287
   Location:243 – 444
   Blast Score: 521

   E1_enzyme_family; Superfamily of activating enzymes (E1) of the ubiquitin-like proteins. This family includes classical ubiquitin-activating enzymes E1, ubiquitin-like (ubl) activating enzymes and other mechanistic homologes, like MoeB, Thif1 and others. The common...

RefSeqs of Annotated Genomes: Build 37.1

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Genome Reference Consortium Human Build 37 (GRCh37), Primary_Assembly

Genomic

1. NC_000019.9

   Range

   34919267..34960797

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   GenBank FASTA Sequence Viewer (Graphics)

2. NT_011109.16 

   Range

   7187485..7229015

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   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (Celera)

Genomic

1. AC_000062.1

   Range

   31631711..31673209

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   GenBank FASTA Sequence Viewer (Graphics)

2. NW_927206.1 

   Range

   7203279..7244777

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   GenBank FASTA Sequence Viewer (Graphics)

Alternate assembly (HuRef)

Genomic

1. AC_000151.1

   Range

   31425935..31467711

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   GenBank FASTA Sequence Viewer (Graphics)

2. NW_001838494.1 

   Range

   37992..79768

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   GenBank FASTA Sequence Viewer (Graphics)