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    pcyt1ba phosphate cytidylyltransferase 1B, choline a [ Danio rerio (zebrafish) ]

    Gene ID: 100001552, updated on 27-Mar-2024

    Summary

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    Official Symbol
    pcyt1baprovided by ZNC
    Official Full Name
    phosphate cytidylyltransferase 1B, choline aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-061220-4
    See related
    Ensembl:ENSDARG00000058162 AllianceGenome:ZFIN:ZDB-GENE-061220-4
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    pcyt1b
    Summary
    Predicted to enable choline-phosphate cytidylyltransferase activity and phosphatidylcholine binding activity. Predicted to act upstream of or within phospholipid biosynthetic process. Orthologous to human PCYT1B (phosphate cytidylyltransferase 1B, choline). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
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    Genomic context

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    Location:
    chromosome: 24
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 24 NC_007135.7 (24922088..24935970)
    105 previous assembly GRCz10 (GCF_000002035.5) 24 NC_007135.6 (24776902..24791087)

    Chromosome 24 - NC_007135.7Genomic Context describing neighboring genes Neighboring gene tripartite motif containing 55b Neighboring gene corticotropin releasing hormone b Neighboring gene pyruvate dehydrogenase kinase, isozyme 3a Neighboring gene solute carrier family 51 member A

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. The Long Noncoding RNA Landscape of Cardiac Regeneration in Zebrafish. Lumley AI, et al. Can J Cardiol, 2021 Mar. PMID 32835855
    2. Expression pattern of the small muscle protein, X-linked (smpx) gene during zebrafish embryonic and larval developmental stages. Ghilardi A, et al. Gene Expr Patterns, 2020 Jun. PMID 32197943
    3. Reconstruction of a 450-My-old ancestral vertebrate protokaryotype. Kohn M, et al. Trends Genet, 2006 Apr. PMID 16517001
    4. Evolution of complexity in the zebrafish synapse proteome. Bayés À, et al. Nat Commun, 2017 Mar 2. PMID 28252024, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables catalytic activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables choline-phosphate cytidylyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables choline-phosphate cytidylyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotidyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables phosphatidylcholine binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within CDP-choline pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    choline-phosphate cytidylyltransferase B
    Names
    phosphate cytidylyltransferase 1, choline, beta a
    NP_001076415.1
    XP_005162722.1
    XP_021325767.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082946.1 → NP_001076415.1  choline-phosphate cytidylyltransferase B

      See identical proteins and their annotated locations for NP_001076415.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133902
      UniProtKB/TrEMBL
      A0A8M1NDJ0, A3KNL3
      Related
      ENSDARP00000065287.6, ENSDART00000065288.7
      Conserved Domains (1) summary
      cd02174
      Location:49 → 198
      CCT; CTP:phosphocholine cytidylyltransferase

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007135.7 Reference GRCz11 Primary Assembly

      Range
      24922088..24935970
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005162665.4 → XP_005162722.1  choline-phosphate cytidylyltransferase B isoform X1

      UniProtKB/TrEMBL
      A0A8M2B9I8
      Conserved Domains (1) summary
      cd02174
      Location:49 → 189
      CCT; CTP:phosphocholine cytidylyltransferase

    2. XM_021470092.1 → XP_021325767.1  choline-phosphate cytidylyltransferase B isoform X2

      UniProtKB/TrEMBL
      A0A8M9P5R2
      Conserved Domains (1) summary
      cl28626
      Location:6 → 239
      PLN02406; ethanolamine-phosphate cytidylyltransferase
    Nucleotide Protein
    Heading Accession and Version

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