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PTPN20A protein tyrosine phosphatase, non-receptor type 20A [ Homo sapiens (human) ]

Gene ID: 653129, discontinued on 12-Apr-2014

Summary

Official Symbol
PTPN20Aprovided by HGNC
Official Full Name
protein tyrosine phosphatase, non-receptor type 20Aprovided by HGNC
Primary source
HGNC:HGNC:23422
See related
MIM:610630
Gene type
protein coding
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT126; PTPN20B; hPTPN20; bA142I17.1
Summary
The product of this gene belongs to the family of classical tyrosine-specific protein tyrosine phosphatases. Many protein tyrosine phosphatases have been shown to regulate fundamental cellular processes and several are mutated in human diseases. Chromosome 10q contains a segmental duplication resulting in multiple copies of the protein tyrosine phosphatase, non-receptor type 20 gene. The two nearly identical copies are designated as PTPN20A and PTPN20B. A third copy is only partially duplicated and contains a pseudogene, designated as PTPN20C. This gene encodes the more centromeric copy, PTPN20A. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
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Genomic context

See PTPN20A in Genome Data Viewer
Location:
10q11.22
Annotation release Status Assembly Chr Location
105 latest, but not current GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (46550123..46641021, complement)
105 latest, but not current CHM1_1.1 (GCF_000306695.2) 10 NC_018921.2 (46619116..46709760, complement)

General protein information

Names
protein tyrosine phosphatase, non-receptor type 20A
cancer/testis antigen 126
tyrosine-protein phosphatase non-receptor type 20