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1996 2
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2005 45
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Page 1
Pharmacokinetics and Pharmacodynamics of Posaconazole.
Chen L, Krekels EHJ, Verweij PE, Buil JB, Knibbe CAJ, Brüggemann RJM. Chen L, et al. Drugs. 2020 May;80(7):671-695. doi: 10.1007/s40265-020-01306-y. Drugs. 2020. PMID: 32323222 Free PMC article. Review.
Posaconazole is typically used for preventing invasive yeast and mold infections such as invasive aspergillosis in high-risk immunocompromised patients. ...As a result, low posaconazole plasma concentrations were obtained in large groups of patients. ...
Posaconazole is typically used for preventing invasive yeast and mold infections such as invasive aspergillosis in high-risk immunoco …
Antifungal agents.
Chen SC, Sorrell TC. Chen SC, et al. Med J Aust. 2007 Oct 1;187(7):404-9. doi: 10.5694/j.1326-5377.2007.tb01313.x. Med J Aust. 2007. PMID: 17908006 Review.
Clinically important "newer" agents include members of the echinocandin class (eg, caspofungin) and second-generation triazoles (eg, voriconazole and posaconazole). Voriconazole and posaconazole have broad-spectrum activity against yeasts and moulds, including Asper …
Clinically important "newer" agents include members of the echinocandin class (eg, caspofungin) and second-generation triazoles (eg, voricon …
Posaconazole.
Keating GM. Keating GM. Drugs. 2005;65(11):1553-67; discussion 1568-9. doi: 10.2165/00003495-200565110-00007. Drugs. 2005. PMID: 16033292 Review.
Posaconazole is a triazole antifungal agent, administered as an oral suspension, with an extended spectrum of in vitro activity. Posaconazole 800 mg/day demonstrated clinically relevant activity against a range of fungi in patients with invasive fungal infections wh …
Posaconazole is a triazole antifungal agent, administered as an oral suspension, with an extended spectrum of in vitro activity. P …
Management of Venetoclax-Posaconazole Interaction in Acute Myeloid Leukemia Patients: Evaluation of Dose Adjustments.
Agarwal SK, DiNardo CD, Potluri J, Dunbar M, Kantarjian HM, Humerickhouse RA, Wong SL, Menon RM, Konopleva MY, Salem AH. Agarwal SK, et al. Clin Ther. 2017 Feb;39(2):359-367. doi: 10.1016/j.clinthera.2017.01.003. Epub 2017 Feb 1. Clin Ther. 2017. PMID: 28161120 Clinical Trial.
When adjusted for different doses and nonlinearity, posaconazole was estimated to increase venetoclax C(max) and AUC(0-24) by 7.1- and 8.8-fold, respectively. ...Posaconazole can be used for antifungal prophylaxis in patients with acute myeloid leukemia receiving ve …
When adjusted for different doses and nonlinearity, posaconazole was estimated to increase venetoclax C(max) and AUC(0-24) by 7.1- an …
Posaconazole-induced Pseudohyperaldosteronism.
Tantiprawan J, Sunthornyothin S, Boonchaya-Anant P, Snabboon T. Tantiprawan J, et al. Kaohsiung J Med Sci. 2021 Mar;37(3):253-254. doi: 10.1002/kjm2.12325. Epub 2020 Nov 24. Kaohsiung J Med Sci. 2021. PMID: 33231362 Free article. No abstract available.
Posaconazole in immunocompromised pediatric patients.
Vicenzi EB, Cesaro S. Vicenzi EB, et al. Expert Rev Anti Infect Ther. 2018 Jul;16(7):543-553. doi: 10.1080/14787210.2018.1490177. Epub 2018 Jul 3. Expert Rev Anti Infect Ther. 2018. PMID: 29912581 Review.
Posaconazole is a broad-spectrum triazole widely used to prevent and treat invasive mycoses in adults. ...We found that posaconazole is well tolerated in children with a low incidence of adverse effects. ...
Posaconazole is a broad-spectrum triazole widely used to prevent and treat invasive mycoses in adults. ...We found that posaconazo …
A Review of Population Pharmacokinetic Models of Posaconazole.
Ding Q, Huang S, Sun Z, Chen K, Li X, Pei Q. Ding Q, et al. Drug Des Devel Ther. 2022 Oct 20;16:3691-3709. doi: 10.2147/DDDT.S384637. eCollection 2022. Drug Des Devel Ther. 2022. PMID: 36277600 Free PMC article. Review.
Posaconazole is often used for the prophylaxis and treatment of invasive fungal infections (IFI). ...This review aimed to comprehensively summarize the published PopPK models of posaconazole and analyze covariates that significantly influence posaconazole exp …
Posaconazole is often used for the prophylaxis and treatment of invasive fungal infections (IFI). ...This review aimed to comprehensi …
Pharmacokinetic/pharmacodynamic profile of posaconazole.
Li Y, Theuretzbacher U, Clancy CJ, Nguyen MH, Derendorf H. Li Y, et al. Clin Pharmacokinet. 2010 Jun;49(6):379-96. doi: 10.2165/11319340-000000000-00000. Clin Pharmacokinet. 2010. PMID: 20481649 Review.
Therefore, inhibitors or inducers of these clearance pathways may affect posaconazole plasma concentrations. Since posaconazole is an inhibitor primarily of CYP3A4, plasma concentrations of drugs that are predominantly metabolized by CYP3A4 may be increased by po …
Therefore, inhibitors or inducers of these clearance pathways may affect posaconazole plasma concentrations. Since posaconazole …
Conazoles.
Heeres J, Meerpoel L, Lewi P. Heeres J, et al. Molecules. 2010 Jun 9;15(6):4129-88. doi: 10.3390/molecules15064129. Molecules. 2010. PMID: 20657432 Free PMC article. Review.
The attractive in vitro antifungal spectrum was a starting point to design more potent and especially orally active antifungal agents such as ketoconazole, itraconazole, posaconazole, fluconazole and voriconazole. The chemistry, in vitro and in vivo antifungal activity, …
The attractive in vitro antifungal spectrum was a starting point to design more potent and especially orally active antifungal agents such a …
Pharmacologic and clinical evaluation of posaconazole.
Moore JN, Healy JR, Kraft WK. Moore JN, et al. Expert Rev Clin Pharmacol. 2015 May;8(3):321-34. doi: 10.1586/17512433.2015.1034689. Expert Rev Clin Pharmacol. 2015. PMID: 25916666 Free PMC article. Review.
Posaconazole, a broad-spectrum triazole antifungal agent, is approved for the prevention of invasive aspergillosis and candidiasis in addition to the treatment of oropharyngeal candidiasis. ...This review will examine the development history of posaconazole and high …
Posaconazole, a broad-spectrum triazole antifungal agent, is approved for the prevention of invasive aspergillosis and candidiasis in …
2,160 results